Results 211 to 220 of about 1,182 (265)

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai   +7 more
wiley   +1 more source

Haploid Mutation Mapping Identifies a Homoeologous Non‐Reciprocal Translocation Linked to Reduced Fibre and Enhanced Protein in Brassica napus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT A key challenge for the genetic improvement of canola (Brassica napus), one of the world's most important oilseeds, is the limited natural variation for commercially important traits. The creation of new variation is hindered by the lack of functional knowledge about genes controlling these traits.
Morgan W. Kirzinger   +30 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

open access: yesPhotochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima   +6 more
wiley   +1 more source

Reparations after species extinctions: An account of reparative interspecies justice

open access: yes
Journal of Social Philosophy, EarlyView.
Anna Wienhues, Alfonso Donoso
wiley   +1 more source

The Gradability of ‘Conscious’

open access: yesPhilosophy and Phenomenological Research, EarlyView.
ABSTRACT Are some creatures “more conscious” than others? A number of consciousness researchers have aimed to answer this question. Yet some have claimed that this question does not even make sense. They claim that “conscious” (in the phenomenal sense) never occurs as a gradable adjective, meaning an adjective that permits degree expressions (“more f ...
Andrew Y. Lee, Poppy Mankowitz
wiley   +1 more source

The transmembrane protein Syndecan is required for stem cell survival and maintenance of their nuclear properties. [PDF]

open access: yesPLoS Genet
Eldridge-Thomas BL   +6 more
europepmc   +1 more source

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