Results 201 to 210 of about 2,369,262 (399)

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Safety and Immunogenicity of an Enterotoxigenic Escherichia coli Vaccine Patch Containing Heat-Labile Toxin: Use of Skin Pretreatment To Disrupt the Stratum Corneum

, 2007
Gregory M. Glenn, Christina P. Villar, David C. Flyer, A. Louis Bourgeois, Robin McKenzie, Robert M. Lavker, Sarah A. Frech   +6 more
openalex   +1 more source

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Crosstalk of Escherichia coli FadR with Global Regulators in Expression of Fatty Acid Transport Genes

, 2012
Youjun Feng, John E. Cronan
openalex   +1 more source

Solitary BioY Proteins Mediate Biotin Transport into Recombinant Escherichia coli [PDF]

, 2013
Friedrich Finkenwirth, F.W. Kirsch, Thomas Eitinger   +2 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Mucosal immunization of piglets with purified F18 fimbriae does not protect against F18(+) Escherichia coli infection [PDF]

, 2007
CLEMENTSD, J, Cox, Eric, Goddeeris, Bruno, LYCKE, N, Tiels, Petra, VAN GOG, K, Verdonck, Frank   +6 more
core   +1 more source

Detrimental impact of silica nanoparticles on the nanomechanical properties of Escherichia coli, studied by AFM

, 2018
Marion Mathelié‐Guinlet, Christine Grauby‐Heywang, Axel Martin, Hugo Février, Fabien Moroté, Alexandre Vilquin, Laure Béven, Marie‐Hélène Delville, Touria Cohen-Bouhacina   +8 more
openalex   +2 more sources

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

Advanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo, Zihua Guo, Yi Zhou, Yunhui Zhang, Haojin Cheng, Rebecca Devine, Chuang Sun, Ronghua Liu, Yanfen Zheng, Andrew J. Gates, Jonathan D. Todd, Xiao‐Hua Zhang   +11 more
wiley   +1 more source

Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure–activity study

, 2012
Erik Chorell, Jerome S. Pinkner, Christoffer Bengtsson, Thomas Sainte‐Luce Banchelin, Sofie Edvinsson, Anna Linusson, Scott J. Hultgren, Fredrik Almqvist   +7 more
openalex   +1 more source