Results 201 to 210 of about 28,813 (238)

Roles of DNA Damage Response Pathway in the Regulation of the Nuclear Envelope. [PDF]

open access: yesCurr Issues Mol Biol
Kamikawa Y   +4 more
europepmc   +1 more source
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ESCRTs and human disease

Biochemical Society Transactions, 2009
The ESCRT (endosomal sorting complex required for transport) machinery plays a critical role in receptor down-regulation, retroviral budding, and other normal and pathological processes. The ESCRT components are conserved in all five major subgroups of eukaryotes.
Suraj, Saksena, Scott D, Emr
openaire   +2 more sources

ESCRTing membrane collapse

Nature Reviews Molecular Cell Biology, 2020
Vietri et al. show that failure to repair micronuclear membranes is caused by unrestrained activity of ESCRT-III.
openaire   +2 more sources

Piecing together the ESCRTs

Biochemical Society Transactions, 2009
High-resolution structural analysis has characterized nearly all of the individual domains of ESCRT (endosomal sorting complex required for transport) subunits, all of the core structures of the soluble complexes and many of the interactions involving domains.
James H, Hurley   +5 more
openaire   +2 more sources

The many functions of ESCRTs

Nature Reviews Molecular Cell Biology, 2019
Cellular membranes can form two principally different involutions, which either exclude or contain cytosol. The 'classical' budding reactions, such as those occurring during endocytosis or formation of exocytic vesicles, involve proteins that assemble on the cytosol-excluding face of the bud neck.
Harald A Stenmark, Maja Radulovic
exaly   +3 more sources

Shaping development with ESCRTs

Nature Cell Biology, 2011
Originally identified for their involvement in endosomal sorting and multivesicular endosome (MVE) biogenesis, components of the endosomal sorting complex required for transport (ESCRT) are now known to control additional cellular functions such as receptor signalling, cytokinesis, autophagy, polarity, migration, miRNA activity and mRNA transport.
T. E. Rusten, T. Vaccari, H. Stenmark
openaire   +2 more sources

ESCRTs offer repair service

Science, 2018
A cellular membrane remodeling machinery repairs damaged ...
Maximiliano G, Gutierrez   +1 more
openaire   +2 more sources

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