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Apolipoprotein-L Functions in Membrane Remodeling [PDF]

Cells
The mammalian Apolipoprotein-L families (APOLs) contain several isoforms of membrane-interacting proteins, some of which are involved in the control of membrane dynamics (traffic, fission and fusion). Specifically, human APOL1 and APOL3 appear to control
Etienne Pays
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ESCRT-III: a versatile membrane remodeling machinery and its implications in cellular processes and diseases

Animal Cells and Systems
The endosomal sorting complexes required for transport (ESCRT) machinery is an evolutionarily conserved cytosolic protein complex that plays a crucial role in membrane remodeling and scission events across eukaryotes.
Jisoo Park, Jongyoon Kim, Hyungsun Park, Taewan Kim, Seongju Lee   +4 more
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Mitochondrial Membrane Remodeling

Frontiers in Bioengineering and Biotechnology, 2022
Mitochondria are key regulators of many important cellular processes and their dysfunction has been implicated in a large number of human disorders.
Ziyun Yang, Ziyun Yang, Ziyun Yang, Liang Wang, Cheng Yang, Cheng Yang, Cheng Yang, Shiming Pu, Shiming Pu, Shiming Pu, Ziqi Guo, Ziqi Guo, Ziqi Guo, Qiong Wu, Qiong Wu, Qiong Wu, Zuping Zhou, Zuping Zhou, Zuping Zhou, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao   +22 more
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Membrane Remodeling by Arc/Arg3.1

Frontiers in Molecular Biosciences, 2021
The activity-regulated cytoskeletal-associated protein (Arc, also known as Arg3.1) is an immediate early gene product induced by activity/experience and required for multiple modes of synaptic plasticity.
Per Niklas Hedde, Per Niklas Hedde, Leonel Malacrida, Leonel Malacrida, Barbara Barylko, Derk D. Binns, Joseph P. Albanesi, David M. Jameson   +7 more
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Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity

Frontiers in Microbiology, 2021
Selective cargo packaging into bacterial extracellular vesicles has been reported and implicated in many biological processes, however, the mechanism behind the selectivity has remained largely unexplored.
Nichole Orench-Rivera, Meta J. Kuehn
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Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts

Scientific Reports, 2021
Recent studies identified cyclase-associated proteins (CAPs) as important regulators of actin dynamics that control assembly and disassembly of actin filaments (F-actin).
Lara-Jane Kepser, Sharof Khudayberdiev, Laura Soto Hinojosa, Chiara Macchi, Massimiliano Ruscica, Elena Marcello, Carsten Culmsee, Robert Grosse, Marco B. Rust   +8 more
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A Putative Lipid-Associating Motif in the West Nile Virus NS4A Protein Is Required for Efficient Virus Replication

Frontiers in Cell and Developmental Biology, 2021
Flavivirus replication is intimately associated with re-organized cellular membranes. These virus-induced changes in membrane architecture form three distinct membranous “organelles” that have specific functions during the flavivirus life cycle.
Andrea Mikulasova, Leah K. Gillespie, Rebecca L. Ambrose, Turgut E. Aktepe, Alice M. Trenerry, Susann Liebscher, Jason M. Mackenzie   +6 more
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Lipid droplets are versatile organelles involved in plant development and plant response to environmental changes

Frontiers in Plant Science, 2023
Since decades plant lipid droplets (LDs) are described as storage organelles accumulated in seeds to provide energy for seedling growth after germination. Indeed, LDs are the site of accumulation for neutral lipids, predominantly triacylglycerols (TAGs),
Imen Bouchnak, Denis Coulon, Vincent Salis, Sabine D’Andréa, Claire Bréhélin   +4 more
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Optimizing Gō-MARTINI Coarse-Grained Model for F-BAR Protein on Lipid Membrane

Frontiers in Molecular Biosciences, 2021
Coarse-grained (CG) molecular dynamics (MD) simulations allow us to access much larger length and time scales than atomistic MD simulations, providing an attractive alternative to the conventional simulations.
Md. Iqbal Mahmood, Adolfo B. Poma, Kei-ichi Okazaki   +2 more
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Computational Approaches to Explore Bacterial Toxin Entry into the Host Cell

Toxins, 2021
Many bacteria secrete toxic protein complexes that modify and disrupt essential processes in the infected cell that can lead to cell death. To conduct their action, these toxins often need to cross the cell membrane and reach a specific substrate inside ...
Weria Pezeshkian, Julian C. Shillcock, John H. Ipsen   +2 more
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