Improvements in functioning and workplace productivity with esketamine nasal spray versus quetiapine extended release in patients with treatment resistant depression:Findings from a 32-week randomised, open-label, rater-blinded phase IIIb study [PDF]
Patients with treatment resistant depression (TRD) experience a greater negative impact on their functioning and productivity at home and in the workplace versus treatment-responsive patients.
Cleare, Anthony
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Oral esketamine for patients with severe treatment-resistant depression:Effectiveness, safety, and tolerability of a six-week open-label treatment program [PDF]
Background: Oral esketamine for patients with treatment-resistant depression (TRD) could offer certain advantages over other routes, such as intravenous or intranasal, but it has not been systematically studied in a real-world setting.
Kamphuis, Jeanine +5 more
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Safety and tolerability of esketamine nasal spray versus quetiapine extended release in patients with treatment resistant depression [PDF]
Funding Information: This study was sponsored by Janssen EMEA. Support for third\u2011party writing assistance for this article, provided by Phoebe Kennedy, MSc, and Andrew Wilhelmsen, PhD, Costello Medical, UK, was funded by Janssen EMEA in accordance ...
Bitter, Istvan +11 more
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Ketamine in Prevention and Treatment of Postpartum Depression - Literature Review [PDF]
Introduction and purpose: Ketamine, used as an anesthetic and analgesic, has gained considerable attention in recent years in the context of treating various psychiatric disorders, particularly the treatment of drug-resistant depression.
Chról, Michał +8 more
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Frontiers in PsychiatryBackgroundNasal esketamine has demonstrated efficacy in the management of treatment-resistant depression and psychiatric emergency due to major depression.
Ahmad H. Almadani +12 more
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Esketamine in Treatment-Resistant Depression and Suicidal Ideation: A Systematic Review [PDF]
Background. Major depressive disorder affects 20% of the global population, with treatment-resistant depression in 10-30% of cases. Patients with acute suicidal ideation need immediate intervention, yet conventional antidepressants require weeks to work.
Drozd, Zuzanna +8 more
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BMC Pregnancy and ChildbirthBackground Postpartum depression (PPD) is categorized by the Disorders-Fifth Edition as depression that begins during pregnancy or within the first month after giving birth. Ketamine and esketamine have shown promising results in the treatment of several
Moaz Yasser Darwish +8 more
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Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression [PDF]
, 2016 Bangkun Yang +8 more
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Comparative safety of prescribed Esketamine and ketamine in relation to renal and urinary disorders : A pharmacovigilance perspective [PDF]
© 2024 The Author(s). Published by Elsevier Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International License (CC BY-NC), https://creativecommons.org/licenses/by-nc/4.0/Intranasal
Arillotta, D +11 more
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Frontiers in PharmacologyBackgroundPostoperative pain following cesarean section can cause maternal anxiety, limited ambulation, and even postpartum depression. In this study, we aimed to investigate the effects of esketamine for postoperative patient-controlled intravenous ...
Yanping Zhao +3 more
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