Results 61 to 70 of about 5,221 (170)

Effect of low-dose esketamine on cardio-biliary reflex and postoperative pain during laparoscopic cholecystectomy surgery: A randomized, controlled trail.

PLoS ONE
BackgroundCardio-biliary reflex can lead to cardiac arrest, brady-arrhythmia, cardiogenic shock, and other severe complications. NMDA receptor antagonists have been shown to have the effect of anti-vagal reflex. However, the regulation of vagus reflex by
Xiaodong Zhang, Peng Duan, Yingjie Sun, Qi Na   +3 more
doaj   +1 more source

Intraoperative esketamine infusion and postoperative sleep quality after shoulder arthroscopy: a randomized controlled trial

Frontiers in Pharmacology
BackgroundSleep disturbance is common after shoulder arthroscopy and may impair postoperative recovery. Whether intraoperative esketamine infusion improves postoperative sleep quality in this population remains unclear.MethodsIn this single-center ...
Chaohui Liu, Wenying Lu, Lifeng Ni, Shengjie Yao   +3 more
doaj   +1 more source

The 90% effective dose (ED90) of esketamine for inhibiting responses to intraoperative motor stimulation during ambulatory hysteroscopy: a biased-coin up-and-down sequential allocation trial

BMC Anesthesiology
Background Esketamine and remimazolam co-administration presents a viable opioid-free anesthetic alternative for outpatient hysteroscopy. This study was designed to ascertain the ED90 of esketamine for inhibiting intraoperative movement responses in ...
Ruiqi Zhang, Chen Wang, Lin Wang, Wenyue Kang, Zhihua Wang   +4 more
doaj   +1 more source

The perspectives of patients with depression toward esketamine, and the influence of their medication adherence on their viewpoints: a Saudi cross-sectional study

Frontiers in Psychiatry
BackgroundNasal esketamine has demonstrated efficacy in the management of treatment-resistant depression and psychiatric emergency due to major depression.
Ahmad H. Almadani, Ahmad H. Almadani, Ayedh H. Alghamdi, Ayedh H. Alghamdi, Fahad B. Alfahad, Abdullah S. Alibrahim, Abdulrahman I. Binbakhit, Ziyad B. Alenazi, Lama M. Alruwaili, Abdulrahman A. Alshahwan, Abdullah K. Muhnna, Mohammed A. Aljaffer, Mohammed A. Aljaffer   +12 more
doaj   +1 more source

Auto-Induction in Oral Esketamine Treatment for Treatment-Resistant Depression: An Exploratory Study

Pharmaceuticals
Background: Esketamine is a rapidly acting antidepressant with robust efficacy in treatment-resistant depression (TRD). Diminishing therapeutic effects and attenuated side effects have been reported after long-term use.
Jolien K. E. Veraart, Cornelis F. Vos, Nieko C. Punt, Dylan Visser, Mireille A. Wessels, Sanne Y. Smith-Apeldoorn, Jeanine Kamphuis, Robert A. Schoevers, Daan J. Touw   +8 more
doaj   +1 more source

Dose-dependent effects of esketamine on the prevention of propofol-induced injection pain: a randomized controlled trial

BMC Anesthesiology
Background In our previous study, we showed that a low dose of esketamine could alleviate propofol-induced injection pain during general anesthesia induction. However, the dose-response relationship of esketamine remains unclear.
Danyun Fu, Yilei Shen, Hongyan Xiao, Jie Jia   +3 more
doaj   +1 more source

Effects of esketamine–sufentanil for patient-controlled intravenous analgesia in women following cesarean section: A randomized clinical trial

Frontiers in Pharmacology
BackgroundPostoperative pain following cesarean section can cause maternal anxiety, limited ambulation, and even postpartum depression. In this study, we aimed to investigate the effects of esketamine for postoperative patient-controlled intravenous ...
Yanping Zhao, Lin Liu, Yi Hou, Jiaming Fan   +3 more
doaj   +1 more source

The efficacy and safety of patient-controlled intravenous analgesia with esketamine after total hip arthroplasty: a randomized controlled trial

BMC Anesthesiology
Purpose To evaluate the efficacy and safety of esketamine-based patient-controlled intravenous analgesia following total hip arthroplasty. Methods A total of 135 total hip arthroplasty patients were randomly assigned to one of the three treatment groups:
Song Qu, Wen-Jie Zhang, Hai-Jiao Zhou, Fei Deng, Rui-Juan Liu, Wen-Jun Yan   +5 more
doaj   +1 more source

Comparison of Esketamine/Propofol and Sufentanil/Propofol on Intraoperative Hypoxemia During Bronchoscopy: A Randomized Trial

Drug Design, Development and Therapy
Xiao Huang,1 Xueyang Li,1 Yuan Sun,2 Anshi Wu,1 Pan Ai1 1Department of Anesthesiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Pharmacy, Peking University Third Hospital, Beijing, People’
Huang X, Li X, Sun Y, Wu A, Ai P
doaj  

Intranasal Esketamine Versus Other Pharmacological Strategies in Treatment-Resistant Depression with High Suicide Risk: A Six-Month Naturalistic Study. [PDF]

Clin Pract
de Granda-Beltrán AM, Porras-Segovia A, Núñez-Arias D, Rodríguez-Jover A, Jassir Acosta MP, Courtet P, Baca-García E, Peñuelas-Calvo I.   +7 more
europepmc   +1 more source