Results 51 to 60 of about 5,221 (170)

Esketamine use in real-world clinical practice in patients with treatment-resistant depression

European Psychiatry
Background Esketamine has been shown to produce a major antidepressant response in patients with treatment-resistant depression (TRD). We evaluated the factors associated with achieving remission in these individuals.
Ismael Conejero, Raquel Alvarez García, Alejandro Porras-Segovia, Ana María De Granda Beltrán, Sergio Benavente López, Ezequiel Di Stasio, Lucía Albarracín-García, Jorge Lopez-Castroman, Philippe Courtet, Enrique Baca-Garcia   +9 more
doaj   +1 more source

Pharmacological Management, Safety, and Outcomes in Bipolar Disorder: An Integrated Narrative Review of Clinical and Translational Evidence

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This graph summarizes bipolar disorder management, showing pharmacological treatments including lithium, valproate, antipsychotics, combination therapy, and emerging agents. It links these treatments to outcomes such as relapse reduction, mortality benefits, and cognitive effects, while highlighting safety issues, poor adherence, pregnancy risks, and ...
Gudisa Bereda
wiley   +1 more source

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, Volume 36, Issue 6, Page 617-627, June 2026.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh, Alhasan Altayf, Ayham Qatza, Abubaker Alghazal, Hasan Al‐sakkaf, Muhammed Elhadi   +5 more
wiley   +1 more source

Case report: two cases of rhabdomyolysis following esketamine treatment

Frontiers in Psychiatry
Major depressive disorder is a mental disorder affecting millions of people worldwide. A considerable proportion of patients demonstrate a lack of response to conventional treatment.
René Zeiss, Melissa Schweizer, Bernhard Connemann, Kathrin Malejko   +3 more
doaj   +1 more source

Anesthesia and Postoperative Pain Management in Hip Reconstructions in Children With Neurodevelopmental Conditions: A Proposal for a Peri‐ and Postoperative Pain Management Protocol

Paediatric and Neonatal Pain, Volume 8, Issue 2, June 2026.
ABSTRACT Progressive hip displacement is a common problem in children with neurodevelopmental conditions, often leading to painful dislocation and impaired function. Hip reconstruction may be necessary to maintain containment but these reconstructions are major surgery in this vulnerable population.
Renée A. van Stralen, Susanne D. Verbaas, Jaap Johannes Tolk, Maaike Dirckx, Frank Weber, Thomas G. de Leeuw   +5 more
wiley   +1 more source

Prefrontal neurophysiological changes associated with subanesthetic esketamine accelerating mice emergence from propofol anesthesia

Brain Research Bulletin
Background: Recent studies have demonstrated that subanesthetic dose of ketamine or its S-enantiomer, esketamine, can paradoxically accelerate the recovery of consciousness in rodents following general anesthesia.
Yinying Sun, Bo Li, Yiting Wang, Xuliang Jiang, Su Tang, Jiayi Zhang, Jun Zhang   +6 more
doaj   +1 more source

The effect of low-dose esketamine on maternal depression after cesarean delivery

Journal of Psychosomatic Obstetrics and Gynecology
Objective To assess the impact of low-dose intravenous esketamine on postpartum depression scores in women undergoing cesarean section.Methods In a randomized, double-blind, placebo-controlled trial, 186 women aged 20–50 years receiving epidural ...
Yan Shang, Siyuan Li, Qin Zheng, Tingting Mi, Yuzhu Lv, Lichun Han, Binrong Wang   +6 more
doaj   +1 more source

Effect of esketamine on hypotension in women with preoperative anxiety undergoing elective cesarean section: a randomized, double-blind, controlled trial

Scientific Reports
To investigate the effect of low-doses esketamine on spinal anesthesia-induced hypotension in women with preoperative anxiety undergoing elective cesarean section, the randomized controlled trial enrolled 120 women aged 18–35 years who preoperative State-
Yu Qi, Meiyan Zhou, Yaqi Dong, Wenting Zheng, Qinyu Jiang, Yanyu Li, Xinghe Wang, Jia Sun, Hai Zhou, Zhengquan Hu, Liwei Wang   +10 more
doaj   +1 more source

Effects of sub-anesthetic doses of esketamine on immune function and postoperative negative emotions in acoustic neuroma patients: a randomized clinical trial

Annals of Medicine
Background Patients undergoing acoustic neuroma (AN) surgery often experience postoperative negative emotions, including anxiety, depression, and immune function suppression.
Zheping Chen, Yaozhu Wang, Peilin Cong, Lifeng Wang, Pengcheng Sun, Zhenzhen Li, He Zhang, Guiting Li, Fengmei Jiao, Juan Zhao, Linyan Li, Yuelong Jin, Qianqian Wu, Li Tian, Yanwu Jin   +14 more
doaj   +1 more source

Plasma esketamine and noresketamine levels and antidepressant response with oral esketamine treatment

European Journal of Pharmacology
Oral esketamine has relatively low and variable bioavailability, which may complicate broader use as an antidepressant. This study aimed to investigate associations between different pharmacokinetic outcomes and change in depressive symptoms following oral esketamine administration in patients with treatment-resistant depression.
Jolien K.E. Veraart, Sanne Y. Smith-Apeldoorn, Jeanine Kamphuis, Daan J. Touw, Robert A. Schoevers   +4 more
openaire   +3 more sources