Results 61 to 70 of about 15,738 (196)

Development and Validation of RP-HPLC Method for Simultaneous Estimation of Aspirin and Esomeprazole Magnesium in Tablet Dosage Form

open access: yesJournal of Chemistry, 2013
A simple, specific, precise, and accurate reversed-phase HPLC method was developed and validated for simultaneous estimation of aspirin and esomeprazole magnesium in tablet dosage forms. The separation was achieved by HyperChrom ODS-BP C18 column (200 mm
Dipali Patel   +5 more
doaj   +1 more source

Effect of Concomitant Medications Affecting Gastric pH and Motility on Posaconazole Tablet Pharmacokinetics [PDF]

open access: yes, 2012
Poster presented at: Interscience Conference on Antimicrobial Agents and Chemotherapy (52nd ICAAC) held in San Francisco 9/9-9/12 Background: Posaconazole (POS) oral suspension is an extended-spectrum triazole that should be taken with food to maximize ...
Chang, P.   +5 more
core   +1 more source

Case series: Joubert syndrome and eosinophilic esophagitis

open access: yesJPGN Reports, Volume 7, Issue 2, Page 329-331, May 2026.
Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening   +5 more
wiley   +1 more source

Inside the isomers: the tale of chiral switches [PDF]

open access: yes, 2004
Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Chiral drugs are made up of molecules with the same chemical structure, but different three-dimensional ...
Bochner, F., Foster, D., Somogyi, A.
core   +1 more source

Population Pharmacokinetic Modeling and Exposure‐Response Analyses of Nemtabrutinib in Patients With Hematologic Malignancies

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Nemtabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor under clinical investigation in patients with hematologic malignancies, including chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL). Nemtabrutinib plasma concentration data from 578 patients enrolled in phase 1 and 2 clinical studies, treated with doses from 5 to ...
Chiara C. Kemal   +3 more
wiley   +1 more source

Efficacy of esomeprazole in treating acid-related diseases in Japanese populations

open access: yesClinical and Experimental Gastroenterology, 2012
Mitsushige Sugimoto1, Takahisa Furuta21First Department of Medicine, 2Center for Clinical Research, Hamamatsu University School of Medicine, Shizuoka, JapanAbstract: Esomeprazole (Nexium®; AstraZeneca), the S-isomer of omeprazole, is the first ...
Furuta T, Sugimoto M
doaj  

Clinical and Histopathological Features of Oral Verruciform Xanthoma: A Case Series of Three Patients

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Oral verruciform xanthoma (OVX) is a rare benign lesion of the oral mucosa that often mimics other oral diseases. We report three cases of OVX and describe their clinical and histopathological characteristics. All patients presented with asymptomatic, well‐demarcated verrucous lesions located on the attached gingiva. The patients ranged in age
Taku Kimura   +5 more
wiley   +1 more source

Meta-analyses: Does long-term PPI use increase the risk of gastric premalignant lesions? [PDF]

open access: yes, 2013
Background: Proton pump inhibitors (PPIs) are the most effective agents available for reducing acid secretion. They are used for medical treatment of various acid-related disorders.
Eslami, L., Nasseri-Moghaddam, S.
core  

Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]

open access: yes, 2015
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng   +5 more
core   +3 more sources

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

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