Results 31 to 40 of about 210,346 (221)

The role of LncRNA SNHG3 in human cancers

Discover Oncology
An essential category of non-protein-coding RNA molecules, known as long noncoding RNAs (lncRNAs), are naturally occurring RNA sequences exceeding 200 nucleotides in length.
Jinming Tang, Min Su, Yuhang Xiao, Wei Ou, Wenxiang Wang, Ren-Wang Peng, Zhining Wu   +6 more
doaj   +1 more source

Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China

Cancer Biology & Medicine, 2017
Esophageal cancer is one of the most fatal diseases worldwide mainly because of its rapid progression and poor prognosis. Although the incidence of esophageal adenocarcinoma has markedly risen in North America and Europe in the past several decades ...
He Liang, Jin-Hu Fan, You-Lin Qiao
doaj   +1 more source

MicroRNA-148a-3p suppresses cell proliferation and migration of esophageal carcinoma by targeting CEP55

Cellular & Molecular Biology Letters, 2021
This study evaluated microRNA-148a-3p in esophageal carcinoma cells. The prediction of bioinformatics analysis revealed that microRNA-148a-3p may target CEP55.
Yong Lin, Yushan Chen, Rongqiang Shen, Dingzhu Chen, Yimin Lin   +4 more
doaj   +1 more source

Endoscopic screening for esophageal squamous cell carcinoma [PDF]

, 2013
Esophageal cancer (EC) is the eighth common cancer and the sixth most common cause of death from cancer worldwide. Esophageal squamous cell carcinoma (ESCC) remains the most common type of EC in the developing world and an important health problem in ...
Amiriani, T., Khoshnia, M., Merat, S., Nouroozi, A., Pourshams, A., Roshandel, G., Semnani, S.   +6 more
core  

The role of peroxiredoxins in cancer [PDF]

, 2017
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO, COPPA, Anna, D'INZEO, SONIA, GIANNINI, Giuseppe, NICOLUSSI, Arianna   +4 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]

, 2016
The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin, Garbán, Hermes, Kaufhold, Samantha   +2 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Recurrent laryngeal nerve lymph nodes status prediction after neoadjuvant therapy for thoracic esophageal squamous cell carcinoma

Insights into Imaging
Objectives Accurately predicting recurrent laryngeal nerve lymph nodes (RLNs) status after neoadjuvant therapy is challenging but essential for efficient dissection of RLNs and for lowering local recurrence rates in patients with esophageal cancer ...
Fengze Wu, Chao Luo, Shumin Zhou, Zexue Peng, Guangying Ruan, Xin Yang, Shuqi Li, Wenjie Huang, Lizhi Liu, Jian Zhou, Baodan Liang, Haojiang Li   +11 more
doaj   +1 more source

promoter methylation is associated with prognosis in esophageal squamous cell carcinoma

Tumor Biology, 2017
Esophageal squamous cell carcinoma is a commonly malignant tumor of digestive tract with poor prognosis. Previous studies suggested that forkhead box F2 ( FOXF2 ) could be a candidate gene for assessing and predicting the prognosis of human cancers ...
Xiaoying Chen, Haochang Hu, Jing Liu, Yong Yang, Guili Liu, Xiuru Ying, Yingmin Chen, Bin Li, Cong Ye, Dongping Wu, Shiwei Duan   +10 more
doaj   +1 more source