Results 31 to 40 of about 785,637 (307)

Case Report: A rare successful case of treating cerebral air embolism following the removal of a central venous catheter without intracardiac structural abnormalities

Frontiers in Surgery
BackgroundCerebral air embolism following the removal of a central venous catheter is a rare and often fatal complication, resulting in severe neurological deficits and potentially death.Case presentationWe report a unique case involving a 57-year-old ...
Mingzhe Song, Mingzhe Song, Wenxiang Wang, Wenxiang Wang, Jie Wu, Jie Wu   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa [PDF]

, 2013
Includes abstract.Includes bibliographical references.Oesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring
Matejcic, Marco
core   +1 more source

The role of LncRNA SNHG3 in human cancers

Discover Oncology
An essential category of non-protein-coding RNA molecules, known as long noncoding RNAs (lncRNAs), are naturally occurring RNA sequences exceeding 200 nucleotides in length.
Jinming Tang, Min Su, Yuhang Xiao, Wei Ou, Wenxiang Wang, Ren-Wang Peng, Zhining Wu   +6 more
doaj   +1 more source

Biobanking for Esophageal Squamous Cell Carcinoma

, 2020
Biobanking is important and fundamental for research and personalized medicine in patients with esophageal squamous cell carcinoma. The process often involves prospective collection of surgically obtained tissues (tissue banking) as well as serial blood ...
Lam, AK, Alfred K. Lam
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

promoter methylation is associated with prognosis in esophageal squamous cell carcinoma

Tumor Biology, 2017
Esophageal squamous cell carcinoma is a commonly malignant tumor of digestive tract with poor prognosis. Previous studies suggested that forkhead box F2 ( FOXF2 ) could be a candidate gene for assessing and predicting the prognosis of human cancers ...
Xiaoying Chen, Haochang Hu, Jing Liu, Yong Yang, Guili Liu, Xiuru Ying, Yingmin Chen, Bin Li, Cong Ye, Dongping Wu, Shiwei Duan   +10 more
doaj   +1 more source

Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China

Cancer Biology & Medicine, 2017
Esophageal cancer is one of the most fatal diseases worldwide mainly because of its rapid progression and poor prognosis. Although the incidence of esophageal adenocarcinoma has markedly risen in North America and Europe in the past several decades ...
He Liang, Jin-Hu Fan, You-Lin Qiao
doaj   +1 more source

Use of Tissue Microarray in Esophageal Squamous Cell Carcinoma

, 2020
Tissue microarray (TMA) is widely used for identifying the expression of markers in many tissues from patients with esophageal squamous cell carcinoma.
Lam, AK, Lor, DK, David K. Lor, Alfred K. Lam   +3 more
core   +1 more source