Results 51 to 60 of about 78,845 (337)

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]

, 2013
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Arnold, Dirk, Brenner, Baruch, Galle, Peter R., Gockel, Ines, Klautke, Gunther, Lang, Hauke, Möhler, Markus, Roessler, Hans-Peter, Rödel, Claus, Schimanski, Carl Christoph, Schmidberger, Heinz, Thomaidis, Thomas, Trarbach, Tanja   +12 more
core   +1 more source

Synchronous advanced gastric adenocarcinoma and advanced esophageal squamous cell carcinoma [PDF]

, 2002
CONTEXT: Synchronous associations of esophageal and gastric cancers are not a common finding, especially with differing histological types and both tumors in advanced forms.
Del Grande, José Carlos, Haddad, Chibly Michel, Herbella, Fernando Augusto Mardiros, Lourenço, Laércio Gomes, Possik, Rafael   +4 more
core   +3 more sources

Angiogenesis and Mast Cells Density in Oral and Esophageal Squamous Cell Carcinomas

Acta Medica Iranica, 2020
Despite the similarities between oral and esophageal squamous cell carcinomas (SCCs), the survival rate of this cancer is relatively low in the esophagus compared to the oral cavity.
Sadra Masali, Rosa Miri, Mojgan Alaeddini, Shahroo Etemad-Moghadam, Donia Sadri, Fatemeh Shahsavari   +5 more
doaj   +1 more source

Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]

, 2007
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S., Derakhshan, M.H., Fyfe, V., Hansen, S., Jellum, E., McColl, K.E.L., Melby, K.K., Vollset, S.E.   +7 more
core   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

RFLMDA: A Novel Reinforcement Learning-Based Computational Model for Human MicroRNA-Disease Association Prediction

Biomolecules, 2021
Numerous studies have confirmed that microRNAs play a crucial role in the research of complex human diseases. Identifying the relationship between miRNAs and diseases is important for improving the treatment of complex diseases.
Linqian Cui, You Lu, Jiacheng Sun, Qiming Fu, Xiao Xu, Hongjie Wu, Jianping Chen   +6 more
doaj   +1 more source

Perspective review of what is needed for molecular-specific fluorescence-guided surgery [PDF]

, 2018
Molecular image-guided surgery has the potential for translating the tools of molecular pathology to real-time guidance in surgery. As a whole, there are incredibly positive indicators of growth, including the first United States Food and Drug ...
Achilefu, Samuel, Pogue, Brian W., Rosenthal, Eben L., van Dam, Gooitzen M.   +3 more
core   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Esophageal pulmonary fistula – a rare complication of radiation therapy: a case report

Journal of Medical Case Reports, 2018
Background Esophageal respiratory fistulae are abnormal communications between the esophagus and the respiratory system. They are either congenital or acquired.
Laetitia Buemi, Salvatore Stefanelli, Philippe Bichard, Mickaël Luscher, Minerva Becker   +4 more
doaj   +1 more source