Results 101 to 110 of about 5,331,742 (248)

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

Clinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao, Zheyi Hu, Elizabeth Gibson, Li Zhu, Heather Vezina, Anna G. Kondic   +5 more
wiley   +1 more source

A rare case of azygos arch tumor thrombus in a patient with esophageal squamous cell carcinoma: A case report

Radiology Case Reports
Esophageal cancer (EC) is among the top ten worldwide causes of cancer related morbidity and mortality. Squamous cell carcinoma (SCC) accounts for over 90% of all cases in sub-Saharan Africa [1].
Desalegn Fekadu, Abdi Alemayehu, Biniyam Tefera, Suleyman Fantahun   +3 more
doaj   +1 more source

12-0-Tetradecanoyl phorbol-13-acetate induced differentiation in human lung squamous carcinoma cells. [PDF]

, 1992
Three human lung squamous carcinoma cell lines (NX002, CX140 and CX143) demonstrate features of squamous differentiation including involucrin synthesis and competence to form cornified envelopes.
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core   +1 more source

Visualization of Scattered Tumor Regression Following Neoadjuvant Chemoimmunotherapy With a Novel Intraoperative PET/CT Scanner

Head &Neck, EarlyView.
ABSTRACT Background Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized. Methods A 79‐year‐old female with recurrent left oral tongue SCC (PD‐L122C3 Combined Positive Score 90) who ...
Andreja Radevic, Joaquin Austerlitz, Ashtyn McAdoo, Kyrionna Golliday, Takeshi Takahashi, Mitra Mehrad, Adam J. Rosenberg, Barbara A. Murphy, Eben Rosenthal, Michael C. Topf   +9 more
wiley   +1 more source

miR-378a-5p exerts tumor-suppressive effects on esophageal squamous cell carcinoma after neoadjuvant immunotherapy by downregulating APOC1/CEP55

Scientific Reports
Genetic assessment of tumors following neoadjuvant immunotherapy helps identifying targets that mediate anti-tumor immunity. In this study, we explored dysregulated RNAs in esophageal squamous cell carcinoma samples after neoadjuvant immunotherapy using ...
Yang Pengjie, Jia Rong, Ning Pengfei
doaj   +1 more source

The Correlation between the Expression of Long Non-coding RNA UCA1 andthe Radio-sensitivity of Esophageal Squamous Cell Carcinoma Patients

Guoji laonian yixue zazhi
Objective To explore the correlation between the expression of long non-coding RNA(lncRNA) UCA1 and radiotherapy sensitivity in patients with esophageal squamous cell carcinoma.
Guangpeng Pan, Yanrong Lu
doaj   +1 more source

Robotic‐Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation

Head &Neck, EarlyView.
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera, Avinash Beharry, Karma Lambercy, Pascaline Dübi, Jelena Todic, Christian Simon   +5 more
wiley   +1 more source

The role of human papillomavirus (HPV) E6 proteins as a risk factor for oesophageal cancer [PDF]

, 2007
Includes bibliographical references (leaves 74-83).Oesophageal squamous cell carcinoma (OSCC) is a major cancer in South Africa, affecting mainly black males.
Ross-Innes, Caryn Sarah
core   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

Outcomes and clinical prognostic factors for elderly patients with esophageal squamous cell carcinoma treated after definitive chemoradiotherapy

Zhongguo aizheng zazhi, 2015
Background and purpose: With the increase of aging population, elderly patients (age ≥70 years) with esophageal squamous cell carcinoma occurred more and more. However, few studies have focused on elderly esophageal squamous cell carcinoma patients. This
吕博, 陈赟, 李云海
doaj