Results 81 to 90 of about 5,331,742 (248)

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

Advanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu, Chenguang Liu, Weihong Zheng, Xiaofei Tong, Zhengwei Gui, Zonghong Lu, Sun Ieong, Lin Zhang   +7 more
wiley   +1 more source

Concurrent incidence of esophageal squamous cell carcinoma and gastric adenocarcinoma: a report of three cases

Сибирский онкологический журнал
The purpose of the study was to investigate rare cases of concurrent incidence of esophageal squamous cell carcinoma and gastric adenocarcinoma to develop an effective treatment strategy.Material and Methods. Herein, we present a report of three cases of
E. A. Toneev, N. V. Dengina, D. V. Glumnushina, R. R. Valeeva, M. S. Rudenko, A. A. Martynov, E. P. Anokhina, A. M. Ponomarenko   +7 more
doaj   +1 more source

Genome sequencing in esophageal squamous cell carcinoma

, 2020
Technological advances in the form of next-generation sequencing allow sequencing of large numbers of different DNA sequences in a single/parallel reaction compared to conventional sequencing.
Lam, AK, Pillai, Suja, Maksemous, N, Maksemous, Neven, Lam, Alfred K., Pillai, S   +5 more
core   +1 more source

Impact of Radiotherapy, Chemotherapy and Surgery in Multimodal Treatment of Locally Advanced Esophageal Cancer [PDF]

, 2011
Objectives: It was the aim of this study to assess our institutional experience with definitive chemoradiation (CRT) versus induction chemotherapy followed by CRT with or without surgery (C-CRT/S) in esophageal cancer.
Annina Lemminger, Stahlberg, Katharina, Lemminger, Annina, Claus Belka, Bleif, Martin, Bamberg, Michael, Katharina Stahlberg, Martin Bleif, Belka, Claus, Berger, Bernhard, Bernhard Berger, Michael Bamberg   +11 more
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Pancreatic Metastases of Esophageal Squamous Cell Carcinoma: A Case Report and Review of the Literature

Diagnostics
Esophageal carcinoma is an aggressive cancer with a poor therapeutic response and a significant risk of recurrence after radical resection. It usually metastasizes to the lung, bones, or liver.
Tivadar Bara, Alexandra Georgiana Scurtu, Tivadar Bara, Zsolt Zoltan Fulop, Renata Moriczi, Patricia Simu, Paul Borz, Simona Gurzu   +7 more
doaj   +1 more source

Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma

, 2020
Orthotopic xenograft model recapitulates the faithful organ-specific microenvironment and facilitates analyses involving tumor-stromal interactions that are crucial for developing new-generation cancer therapy. Herein, we describe the detailed rationales
Yu, VZ, Joseph C. Y. Ip, Lam, AK, Lung, ML, Ip, JCY, Maria L. Lung, Ko, JMY, Tao, L, Josephine M. Y. Ko, Lihua Tao, Valen Z. Yu, Alfred K. Lam   +11 more
core   +1 more source

Return‐To‐Work and Working Status After Surgery for Gastric and Esophageal Cancer: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter prospective study of 158 working‐age patients undergoing curative‐intent surgery for gastric or esophageal cancer, 78.5% were working at 18 months. Postoperative appetite loss, financial difficulties, and ≥ 10% weight loss at 6 months were associated with non‐working status.
Kentaro Goto, Shigeo Hisamori, Kohei Ueno, Hiroyasu Abe, Ryosuke Okamura, Hisahiro Hosogi, Yoshito Yamashita, Dai Manaka, Hiroaki Hata, Tatsuto Nishigori, Sanae Nakajima, Michihiro Yamamoto, Koichi Kinoshita, Shintaro Okumura, Masazumi Sakaguchi, Shigeru Tsunoda, Yu Sakagami, Koya Hida, Kazutaka Obama   +18 more
wiley   +1 more source

Immunohistochemistry for Protein Detection in Esophageal Squamous Cell Carcinoma

, 2020
Immunohistochemistry is the identification of a cell protein by a specific antibody targeting that protein. It is the most common ancillary test to study the pathology of cancer.
Kais Kasem, Kasem, K, Lam, AK, Alfred K. Lam   +3 more
core   +1 more source