Results 121 to 130 of about 141,634 (350)

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

Advanced Intelligent Systems, EarlyView.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger, Claus Hultschig, Daniel Baumhoer, Baptiste Ameline, Benjamin Maciej Freyter, Stephan Frank, Jürgen Hench   +6 more
wiley   +1 more source

Endoscopic submucosal dissection for an atypical small verrucous carcinoma: a case report [PDF]

, 2016
BACKGROUND: Esophageal verrucous carcinoma is a rare variant of esophageal squamous cell carcinoma. In most cases, verrucous carcinoma presents as an exophytic, slow-growing mass with an extensive superficial growth pattern.
Kazuki Sumiyama, Koji Matsuda, Masayuki Kato, Munenori Itagaki, Shuji Ito, Sigeharu Hamatani, Takahiro Abe, Yoshio Aizawa, Yosuke Kawahara   +8 more
core   +1 more source

A validated nomogram integrating hematological indicators to predict response to neoadjuvant therapy in esophageal squamous cell carcinoma patients [PDF]

, 2021
Sichao Wang, Zihao Zhou, Dan Tian, Shujie Huang, Ce Wang, Zhen Gao, Xiaosong Ben, Jiming Tang, Liang Xie, Haiyu Zhou, Dongkun Zhang, Ruiqing Shi, Cheng Deng, Weitao Zhuang, Ding Yu, Guibin Qiao   +15 more
openalex   +1 more source

Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing was performed on tumor tissues from triptolide‐treated tumor‐bearing mice. The sequencing results were integrated with data from public databases for comprehensive analysis, and potential regulatory targets of triptolide were identified.
Zhiwen Cao, Lulu Zhang, Wenqiang Zhang, Rong Wan, Xiaogang Peng, Jinyan Xie, Ruru Bai, Jiejing Jin, Changqi Shi, Lan Yan, Xiangyu Guo, Yang Shen, Cheng Lu   +12 more
wiley   +1 more source

Esophageal Papillomatosis Complicated by Squamous Cell Carcinoma

Canadian Journal of Gastroenterology, 2009
Esophageal papillomatosis is a very rare condition that is believed to have a benign clinical course. Recent reports underscore the potential development of a malignancy in association with squamous papillomatosis of the esophagus.
Tan Attila, Anna Fu, Nanda Gopinath, Catherine J Streutker, Norman E Marcon   +4 more
doaj   +1 more source

Prevalence of squamous cell carcinoma of the esophagus in a single tertiary center of South Africa: a cross sectional analytic study

Journal of Public Health in Africa, 2017
The incidence of esophageal cancer varies widely in the world. In the Middle East, Africa, and Asia and parts of Europe, squamous cell carcinoma of the esophagus dominates the esophageal cancer landscape. Worldwide the rates are highest in Northern China,
Mpho Kgomo, Ali A. Elnagar, Jaco Nagel, Taole Mokoena   +3 more
doaj   +1 more source

The role of TMEM26 in disrupting tight junctions and activating NF-κB signaling to promote epithelial-mesenchymal transition in esophageal squamous cell carcinoma

, 2023
Guohu Han, Shuangshuang Zhou, Junjun Shen, Yuanyuan Yang, Xuyu Bian, Yahu Li, Rui Ling, Rongrui Liang, Min Tao   +8 more
openalex   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Macroscopic extent of gastric mucosal atrophy: increased risk factor for esophageal squamous cell carcinoma in Japan

BMC Gastroenterology, 2009
Background We aimed to estimate whether the macroscopic extent of gastric mucosal atrophy is associated with a risk for esophageal squamous cell carcinoma using a case-control study in Japanese subjects, a population known to have a high prevalence of ...
Kobayashi Noritoshi, Kirikoshi Hiroyuki, Abe Yasunobu, Goto Ayumu, Takahashi Hirokazu, Yoneda Masato, Fujita Koji, Yoneda Kyoko, Hosono Kunihiro, Endo Hiroki, Iida Hiroshi, Inamori Masahiko, Akiyama Tomoyuki, Kubota Kensuke, Saito Satoru, Rino Yasushi, Nakajima Atsushi   +16 more
doaj   +1 more source

Genetic polymorphisms of glutathione S-transferase genes GSTP1, GSTM1, and GSTT1 and risk of esophageal and gastric cardia cancers

, 2009
Glutathione S-transferase (GST) enzymes are known to metabolize tobacco-related carcinogens. Previous studies on the association of functional polymorphisms of GST genes with esophageal squamous cell carcinoma have yielded conflicting but overall null ...
Andersson, B., Bahmanyar, S., McCarthy, S., Nyren, O., Ye, W., Zendehdel, K.   +5 more
core   +1 more source