Results 181 to 190 of about 141,634 (350)

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

A retrospective cohort study to observe the efficacy and safety of Endoscopic Submucosal Dissection (ESD) with adjuvant radiotherapy for T1a-MM/T1b-SM Esophageal Squamous Cell Carcinoma (ESCC).

PLoS ONE
Background and aimThe clinical outcome of endoscopy submucosal dissection with subsequent radiotherapy for esophageal squamous cell carcinoma remain unclear.
Hongna Lu, Yanping Bei, Chunnian Wang, Xi Deng, QinQin Hu, Wenying Guo, Xuesong Zhang   +6 more
doaj   +1 more source

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment [PDF]

, 2021
Huy Q. Dinh, Feng Pan, Geng Wang, Qingfeng Huang, Claire Olingy, Zhi‐Yong Wu, Shaohong Wang, Xin Xu, Xiu‐E Xu, Jianzhong He, Qian Yang, Sandra Oršulić, Marcela Haro, Liyan Li, Guowei Huang, Joshua J. Breunig, H. Phillip Koeffler, Catherine C. Hedrick, Li‐Yan Xu, De‐Chen Lin, En‐Min Li   +20 more
openalex   +1 more source

Age‐Adjusted Charlson Comorbidities Index for Survival Prognosis in Laryngeal Squamous Cell Carcinoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study aimed to explore the prognostic relevance of the age‐adjusted Charlson Comorbidity Index (ACCI) in laryngeal squamous cell carcinoma (LSCC) survival. Methods This retrospective analysis was conducted on the medical records of 367 LSCC patients admitted to the First Hospital of Shanxi Medical University, China, from January
Ze‐Hui Gao, Rui Han, Su‐Zhen She, Li‐Na Jia, Hui Huang‐Fu, Huan‐Hai Liu   +5 more
wiley   +1 more source

Orbital Metastasis of Esophageal Squamous Cell Carcinoma

Internal Medicine, 2021
Iimori, Kei, Kou, Tadayuki, Yazumi, Shujiro   +2 more
openaire   +3 more sources

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Expressions of the gamma2 chain of laminin-5 and secreted protein acidic and rich in cysteine in esophageal squamous cell carcinoma and their relation to prognosis

, 2011
Liyan Xue, Shuangmei Zou, Shan Zheng, Xiuyun Liu, Wen Peng, Yanling Yuan, Dongmei Lin, Ning Lü   +7 more
openalex   +2 more sources

Role of vascular endothelial growth factor in radiotherapy resistance to esophageal squamous cell carcinoma

, 2022
Xin Li, Xinyu Su, Yan Chen, Yuanyuan Ma, Heng Li, Jianhong Xia, Hongliang Li, Qian Jiang, Liqing Zhou, Zhengyun Zou   +9 more
openalex   +2 more sources

Prognostic significance of pyruvate kinase M2 expression in esophageal squamous cell carcinoma and its meta-analysis [PDF]

, 2021
Qiqi Zhang, Shutao Zheng, Qing Liu, Tao Liu, Aerziguli Tuerxun, Lifei Yang, Xiujuan Han, Xiaomei Lu   +7 more
openalex   +1 more source