Esophageal Perforation in Zollinger-Ellison Syndrome: A Scoping Review of Management and Outcomes. [PDF]
ABSTRACT Esophageal perforation in Zollinger–Ellison syndrome (ZES) is an exceedingly rare and life‐threatening manifestation of gastrinoma‐related acid hypersecretion. While peptic ulceration and severe reflux are recognized complications of ZES, perforation represents the ultimate consequence of uncontrolled hyperacidity. Evidence remains confined to
Fernicola A +8 more
europepmc +2 more sources
Safety of Potassium-Competitive Acid Blockers Compared With Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease and Peptic Ulcer Disease: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Background and Aim Potassium‐competitive acid blockers (P‐CABs) are a novel class of acid suppressants developed to overcome the limitations of proton pump inhibitors (PPIs), providing rapid and sustained acid suppression. While PPI‐related adverse events (AEs) are well‐documented, safety data on P‐CABs remain limited.
Jang Y +6 more
europepmc +2 more sources
Abstract Diseases of the Gastrointestinal (GI) tract significantly affect the quality of human life and have a high fatality rate. Accurate diagnosis of GI diseases plays a pivotal role in healthcare systems. However, processing large amounts of medical image data can be challenging for radiologists and other medical professionals, increasing the risk ...
Muhammad Nouman Noor +5 more
wiley +1 more source
Tegoprazan Versus Proton Pump Inhibitors for Erosive Esophagitis: A Meta-Analysis of Noninferiority Randomized Controlled Trials. [PDF]
ABSTRACT Purpose Proton pump inhibitors (PPIs) remain the standard treatment option for erosive esophagitis (EE) but have notable limitations due to side effects associated with long‐term use. Tegoprazan, a novel potassium‐competitive acid suppressant (P‐CAB), may provide an alternative treatment option.
Bhatti MI +5 more
europepmc +2 more sources
BackgroundProton-pump inhibitors such as omeprazole are a standard treatment to prevent non-steroidal anti-inflammatory drug-induced upper gastrointestinal mucosal injuries.
T. Kuramoto +13 more
semanticscholar +1 more source
Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S. +3 more
core +2 more sources
An evaluation of 605 endoscopic examination in a rural setting, Lacor Hospital in Northern Uganda [PDF]
Introduction: The aim of this study was to evaluate the profile of esophagogastroduodenal (EGDS) diseases diagnosed by upper endoscopy in a rural area of Uganda in a retro-protective study of 605 patients.
Alema NO +3 more
core +1 more source
Endoscopic evaluation of patients with dyspepsia in a secondary referral hospital in Egypt
Background: Dyspepsia is a common clinical problem. More than half of patients presenting with dyspepsia have no detectable lesion for their symptoms. The common organic causes of dyspepsia include peptic ulcer, esophagitis and cancer.
Ahmed Gado +3 more
doaj +1 more source
Background and Aim The aim of the present study was to examine the lifestyle‐ and comorbidity‐related determinant factors of the prescription of proton pump inhibitors (PPIs) for patients in whom Helicobacter pylori has been eradicated, and to evaluate ...
Furitsu Shimada +13 more
doaj +1 more source
Review – Helicobacter pylori & non-malignant upper GI diseases [PDF]
Helicobacter pylori remains a crucial factor in the development of gastrointestinal (GI) diseases including chronic gastritis, peptic ulcer disease (PUD) and gastric cancer, even decades after its discovery.
V. Ivanova +3 more
doaj +1 more source

