Results 121 to 130 of about 440,397 (404)

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Canine megaesophagus secondary to acetylcholinesterase inhibitors (chumbinho) intoxication: an unusual presentation

Medicina Veterinária, 2020
Megaesophagus is a disease characterized by generalized esophageal dilatation, resulting from reduced or absent esophageal motility. It can be congenital or acquired and some common causes are persistent right aortic arch and myasthenia gravis.
Juliana Roberts Oaskis, Sofia Munaldi Machado, Jórnie Mantovani Cezana, Wanderson Lopes Andrade, Bruna Batista Palácio, Paulo Sérgio Cruz de Andrade Júnior, Camila Barbosa Amaral   +6 more
doaj  

Gastric tube ulcer perforating the pericardium after subtotal esophagectomy [Perforacija ulkusa želučanog supstituta u perikard nakon subtotalne ezofagektomije] [PDF]

, 2013
Subtotal esophagectomy with retrosternal transposition of the gastric tube to the neck was performed in a 62-year-old patient with squamous cell carcinoma of the proximal third of the esophagus.
Korušić, Anđelko, Mikecin, Verica, Nikolić, Igor, Stančić-Rokotov, Dinko, Đuzel, Viktor, Špiček Macan, Jasna   +5 more
core  

Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society

Esophagus, 2014
Purpose These guidelines are intended for doctors who are engaged in the diagnosis and treatment of esophageal carcinoma, for the following purposes: (1) to present the standard practice for the diagnosis and treatment of esophageal carcinoma with a ...
H. Kuwano, Y. Nishimura, T. Oyama, H. Kato, Y. Kitagawa, M. Kusano, H. Shimada, H. Takiuchi, Y. Toh, Y. Doki, Y. Naomoto, H. Matsubara, T. Miyazaki, M. Muto, A. Yanagisawa   +14 more
semanticscholar   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

The assessment of patients with non-erosive gastroesophageal reflux disease by using the Bravo® pH monitoring system

Sanamed, 2022
Background and aim: Gastroesophageal reflux disease (GERD) is a common disease in the world. GERD is always treated with drugs. The Bravo® wireless pH monitoring system is a good technique. The Bravo® may affect increasing the specificity and sensitivity
Gök Mehmet, Gencdal Genco
doaj  

A Chestnut–A Difficult Challenge for an Endoscopist

Journal of Digestive Endoscopy, 2019
True foreign bodies are a frequent problem in mentally disabled adults and since ingestion is usually intentional, retrieval can be difficult due to unusual, previously in practice not encountered objects.
Dalia Zykutė, Romanas Zykus
doaj   +1 more source

The Esophagus and Its Diseases. [PDF]

, 1953

openalex   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source