Results 61 to 70 of about 347,041 (314)

Clinical outcomes of EGFR-TKI in advanced lung squamous cell carcinoma and EGFR-TKI remodel tumor immune microenvironment

open access: yesAnnals of Medicine
Background Clinical data is scarce in epidermal growth factor receptor (EGFR)-mutated lung squamous cell carcinoma (LUSC), and the resistance mechanisms to EGFR-tyrosine kinase inhibitor (TKI) is rarely studied. This study aimed to assess the efficacy of
Zhixin Chen   +6 more
doaj   +1 more source

Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]

open access: yes, 2019
Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian   +9 more
core   +2 more sources

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung   +7 more
wiley   +1 more source

Pulmonary salivary gland tumor–hyalinizing clear cell carcinoma: a literature review

open access: yesDiagnostic Pathology
Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a very rare lung tumor that accounts for less than 0.09% of all primary lung tumors and has no specific epidemiology.
Xinyuan Wang, Shumin Hu, Hongyang Lu
doaj   +1 more source

A formal theory for spatial representation and reasoning in biomedical ontologies [PDF]

open access: yes, 2006
Objective: The objective of this paper is to demonstrate how a formal spatial theory can be used as an important tool for disambiguating the spatial information embodied in biomedical ontologies and for enhancing their automatic reasoning capabilities ...
Bittner, Thomas   +2 more
core   +2 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo   +19 more
wiley   +1 more source

Risk factors of esophageal cancer in Turkmen Sahra of Iran [PDF]

open access: yes, 2007
Present study was carried out in three years' duration (2002-2004) to investigate the risk factors of esophageal cancer in Iranian Turkmens (Northeast of Iran; where the esophageal cancer is the most common world wide).
Besharat, S.   +3 more
core  

Gastroesophageal reflux disease and tooth erosion [PDF]

open access: yes, 2011
The increasing prevalence of gastroesophageal reflux disease (GERD) in children and adults, and of “silent refluxers” in particular, increases the responsibility of dentists to be alert to this potentially severe condition when observing unexplained ...
Kaidonis, J., Ranjitkar, S., Smales, R.
core   +4 more sources

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula   +1 more
wiley   +1 more source

MAGTWIST: A Magnetically‐Driven Rotary Actuator Using a Traveling‐Wave With Integrated Stiffness Tunability

open access: yesAdvanced Functional Materials, EarlyView.
MAGTWIST: A compact magnetic rotary actuator, enabling smooth, stepless rotation, and on‐demand locking. Inspired by peristalsis, a soft polymer belt generates a traveling‐wave, enabling 270° rotation when heated. Cooling stiffens the belt, locking it in position and enabling it to withstand high loads.
Simon Frieler   +3 more
wiley   +1 more source

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