Results 61 to 70 of about 367,034 (414)

Geometry-Aware Latent Representation Learning for Modeling Disease Progression of Barrett's Esophagus [PDF]

arXiv, 2023
Barrett's Esophagus (BE) is the only precursor known to Esophageal Adenocarcinoma (EAC), a type of esophageal cancer with poor prognosis upon diagnosis. Therefore, diagnosing BE is crucial in preventing and treating esophageal cancer. While supervised machine learning supports BE diagnosis, high interobserver variability in histopathological training ...
arxiv  

Radiofrequency ablation in Barrett's esophagus with dysplasia.

New England Journal of Medicine, 2009
BACKGROUND Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma.
N. Shaheen, Prateek Sharma, B. Overholt, H. Wolfsen, R. Sampliner, Kenneth K Wang, J. Galanko, M. Bronner, J. Goldblum, A. Bennett, B. Jobe, G. Eisen, M. Fennerty, J. Hunter, D. Fleischer, V. Sharma, R. Hawes, B. Hoffman, R. Rothstein, S. Gordon, H. Mashimo, K. Chang, V. Muthusamy, S. Edmundowicz, S. Spechler, A. Siddiqui, R. Souza, A. Infantolino, G. Falk, M. Kimmey, R. Madanick, A. Chak, C. Lightdale   +32 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Review of esophageal injuries and stenosis: Lessons learn and current concepts of management

Journal of Indian Association of Pediatric Surgeons, 2016
Aim: To review the patients with esophageal injuries and stenosis with respect to their etiology, clinical course, management, and the lessons learnt from these.
Raghu Sampalli Ramareddy, Anand Alladi
doaj   +1 more source

Large Language Models for Granularized Barrett's Esophagus Diagnosis Classification [PDF]

arXiv, 2023
Diagnostic codes for Barrett's esophagus (BE), a precursor to esophageal cancer, lack granularity and precision for many research or clinical use cases. Laborious manual chart review is required to extract key diagnostic phenotypes from BE pathology reports. We developed a generalizable transformer-based method to automate data extraction.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Radiographic and ultrasonographic evaluation of the esophagus in the horse [PDF]

, 2016
The purpose of this study was to describe the radiographic and ultrasonographic appearance of the esophagus of ten healthy horses. Contrast radiography showed variations in the long-axis shape of the esophagus at the thoracic inlet.
Palmers, K, Pardon, Bart, Paulussen, Ellen, Picavet, MT, Van der Vekens, Elke, van Loon, Gunther   +5 more
core  

Optimizing Storage and Computational Efficiency: An Efficient Algorithm for Whole Slide Image Size Reduction

Mayo Clinic Proceedings: Digital Health, 2023
Objective: To efficiently store, transfer, and analyze whole slide imaging (WSI), we developed an image-processing algorithm to remove the unneeded background in a WSI and assemble tissue-containing parts into smaller WSIs without any change in tissue ...
Shahriar Faghani, MD, D. Chamil Codipilly, MD, Mana Moassefi, MD, Prasad G. Iyer, MD, Bradley J. Erickson, MD, PhD   +4 more
doaj  

Microbial Similarity and Preference for Specific Sites in Healthy Oral Cavity and Esophagus

Frontiers in Microbiology, 2018
Human microbial communities are highly complex ecosystems, but it remains unclear if microbial compositions have any similarity in distinct sites of the oral cavity and esophagus in particular.
Li Dong, J. Yin, J. Zhao, Shanrui Ma, Hai-rui Wang, Meng Wang, W. Chen, Wenqiang Wei   +7 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source