Results 141 to 150 of about 4,634,175 (249)

Immunomodulatory activity of Zingiber officinale Roscoe, Salvia officinalis L. and Syzygium aromaticum L. essential oils: evidence for humor- and cell-mediated responses [PDF]

, 2009
Fábio Ricardo Carrasco, Gustavo Schmidt, Adriano Lopes Romero, Juliano L. Sartoretto, Silvana Martins Caparroz‐Assef, Ciomar Aparecida Bersani‐Amado, Roberto Kenji Nakamura Cuman   +6 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Study of Antibiotic Resistance Potential of Spiders Bacteriota and Comparison With the Antibacterial Effect of Essential Oils. [PDF]

Microbiologyopen
Kačániová M, Elizondo-Luevano JH, Ban Z, Babošová M, Porhajašová JI, Kollár J, Kowalczewski PŁ, Garzoli S.   +7 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Larvicidal Activities of <i>Juniperus chinensis</i> var. <i>kaizuka</i> Leaf Essential Oil and Its Constituents Against Dengue Vector Mosquitoes, <i>Aedes aegypti</i> and <i>Ae. albopictus</i>. [PDF]

Plants (Basel)
Chang JY, Tsai KH, Huang YM, Chang YY, Huang CS, Ho YT, Wang SY, Chang ML, Chang HT.   +8 more
europepmc   +1 more source

Mutational Analysis of Essential Interactions Involved in the Assembly of Hepatitis E Virus Capsid [PDF]

, 2004
Shaowei Li, Jun Zhang, Zhiqiang He, Ying Gu, Ru‐Shi Liu, Jian Lin, Yixin Chen, Mun‐Hon Ng, Ningshao Xia   +8 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Seasonal and Regional Effects on the Yield and Bioactive Constituents of <i>Torreya nucifera</i> Essential Oils in South Korea. [PDF]

Plants (Basel)
Park C, Kim N, Park MJ.
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Treatment with Thyme Essential Oil Delays Loss Reductions in Postharvest Chinese Flowering Cabbage. [PDF]

Foods
Chen D, Li M, Wu W, Wang L, Chen Y, Wu F.   +5 more
europepmc   +1 more source