Results 161 to 170 of about 13,121,660 (348)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Landscape of Gene Essentiality in Cancer Cell Death Pathways. [PDF]

open access: yesGenes (Basel)
Li S   +5 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Thyme essential oil for sheep: effect on rumen fermentation, nutrient digestibility, nitrogen metabolism, and growth

open access: green, 2019
Angelo Dias Brito Ribeiro   +7 more
openalex   +1 more source

VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis [PDF]

open access: hybrid, 2015
Jessica C. Nicholson-Fish   +4 more
openalex   +1 more source

An Exploratory Analysis of Essential Tremor and Associated Phenotypes. [PDF]

open access: yesTremor Other Hyperkinet Mov (N Y)
Gharibian D   +3 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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