Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Enhancing the anticancer potential of garlic and lemon essential oils through nanoemulsification: a comparative study. [PDF]
Elgendy EM +3 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Ancient Essential Oils: Exploring the Effects of Age on Bioactivity
It seems reasonable to expect that the molecular composition and bioactivity of essential oils will undergo changes after protracted storage times, reflecting, among other things, the effects of differential evaporation, photo-oxidisation or temperature.
Sadgrove, Nicholas +2 more
core
How the MDGs gave up on measuring access to medicines
Dzintars Gotham +2 more
doaj +1 more source
Fortifying essential medicines supply chains in Sub-Saharan Africa - the curious cases of Kenya and Uganda. [PDF]
Kludze M, Hussein M.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Serotonin content and uptake in platelets can distinguish Parkinson's disease from control patients and essential tremor. [PDF]
Montenegro P +6 more
europepmc +1 more source

