Results 181 to 190 of about 4,819,037 (269)

Effect of Mindfulness Training on the Clinical Pregnancy Rate in Women Undergoing Frozen Embryo Transfer: Study Protocol for a Single-Center, Open-Label, Randomized Controlled Trial. [PDF]

Int J Womens Health
Yi S, Zhang J, Li A, Zhou N, Li J, Cao R, Gao Y, Liu X, Zhai J.   +8 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Antibacterial and Anti-Inflammatory Properties of <i>Citrus aurantiifolia</i> Essential Oil-Based Mouthwash: Potential and Cytotoxicity Concerns. [PDF]

Scientifica (Cairo)
Mulyanti S, Laela DS, Vasall PRN, Permadi N, Aripin D, Amaliya A, Rukayadi Y, Julaeha E.   +7 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The evidence-informed decision-making process of the National Essential Medicines List Committee and Essential Drugs Programme

Journal of the Colleges of Medicine of South Africa
Amanda Brewer, Janine Jugathpal, Kim MacQuilkan, Marc Blockman, Andrew Gray, Tamara Kredo, Reneé de Waal, Lesley Robertson   +7 more
doaj   +1 more source

Larvicidal, oviposition inhibition, electrophysiological, histological, and docking activity of <i>Eugenia uniflora L. oil against Aedes aegypti</i>. [PDF]

Front Pharmacol
Aguiar JVC, de Aguiar JCROF, de Lima EB, da Silva AC, Santos EF, Pereira Júnior PG, Santos GKN, da Rocha SKL, de Andrade JJA, da Silva PS, Vieira GJDSG, Teixeira VW, Cruz GDS, Coelho Teixeira ÁA, de Moraes MM, da Câmara CAG, Milet-Pinheiro P, Marques AM, Figueiredo MR, Navarro DMAF.   +19 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Pioneering Investigation on the Larvicidal Mechanism and Chemical Profile of <i>Piper humillimum</i> C.DC. (Piperaceae) Essential Oil: Integrating <i>In Vivo</i>, <i>In Vitro</i>, and <i>In Silico</i> Models Against <i>Aedes aegypti</i> (Linnaeus, 1762) and <i>Anopheles darlingi</i> Root, 1926 (Culicidae). [PDF]

Molecules
de Oliveira AC, da Costa MLL, Marcusso GM, Simões RC, Serrão RNG, Figueira ÉAG, de Lima GS, Vasconcelos ADS, Marques JA, Koolen HHF, da Silva FMA, Sá ISC, Nunomura RCS, Nunomura SM, Roque RA.   +14 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Weak economic evidence for WHO's essential cancer medicines for Africa. [PDF]

BMJ Glob Health
van der Steege AE, Humuza J, Shyirambere C, Hogerzeil H, Baltussen RMPM.   +4 more
europepmc   +1 more source