Results 191 to 200 of about 13,121,660 (348)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Nutritional enrichment of eggs through essential oil-supplemented laying hen diets and associations with intestinal microbiota. [PDF]

Food Sci Anim Resour
Elal Mus T, Ozcan T, Necla Selvi T, Keser G, Ustuner H, Canbolat O.   +5 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nudeotide sequence of the essential region of bacteriophage P4 [PDF]

, 1984
Ching‐Shwun Lin
openalex   +1 more source

Headspace GC-MS volatiles profiling in leaves of 4 Cymbopogon species and their vapor-phase antibacterial effects. [PDF]

Sci Rep
Wahdan MO, Saber FR, Hassan M, Hassan ME, Farag MA.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Essential Best Practices in Inclusive Schools [PDF]

, 2012
Jorgensen, Cheryl M., McSheehan, Michael, Schuh, Mary, Sonnenmeier, Rae M.   +3 more
core   +1 more source

Multivariate Assessment of Microbiological and Incubation Data from an Experimental Trial Evaluating Essential Oil-Based Sanitizers and Formaldehyde on Hatching Eggs. [PDF]

Pathogens
Dos Santos VM, Oliveira GDS, McManus C.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

“If you can't measure it, you can't manage it” – essential truth, or costly myth? [PDF]

, 2018
Martin Prince
openalex   +1 more source