Results 201 to 210 of about 7,916,692 (304)

The 19th EML as a global standard: an innovative approach or just an opportunity for new and effective medicines?

Journal of Pharmaceutical Policy and Practice, 2015
Nicola Magrini, Lorenzo Moja, Bernadette Cappello, Kees De Joncheere, Gilles Forte   +4 more
doaj   +1 more source

Structural and Compositional Effects of Essential Oils on Silica-Rich Gel Materials for Novel Dental Applications. [PDF]

Polymers (Basel)
Bulut H, Arslan O, Lee CC.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Thymol-Rich Lippia thymoides Mart. & Schauer (Verbenaceae) Essential Oil: Seasonal Chemical Variation, Antioxidant Capacity, Artemia salina Toxicity, and AChE Docking. [PDF]

Chem Biodivers
Cruz JN, Silva SG, Morais AAB, de Lima AB, Gomes ARQ, Hamoy M, Andrade EHA.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mycorrhizal Fungal Inoculation Reshapes Chemotype, Nutritional Status, and Metabolic Signatures to Enhance Bioactivity in <i>Origanum compactum</i> Benth. [PDF]

Plants (Basel)
Youne Oumnia A, Mounia AY, Kaoutar O, Said R, Mohammed B, Kaddouri H, Najib AM, Bacem M, Abdessamad T, Hanane D, Nazameen H, Khan Y, Lahcen O.   +12 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Ultrasound-fabricated thyme essential oil nanoemulsions stabilized by clean-label emulsifiers: Physicochemical properties, antibacterial activity, and food decontamination applications. [PDF]

Ultrason Sonochem
He Q, Yuan S, Bian Y, Zhuang Z, Ding C, Zhang C, Tu C, Lu C, Jiang H.   +8 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Additions and Corrections

Natural Product Communications, 2012
Janne Rojas, Shirley Baldovino, Marietta Vizcaya, Luis B. Rojas, Antonio Morales   +4 more
doaj   +1 more source