Results 221 to 230 of about 7,916,692 (304)

Proceedings of the convention on Essential Health Research in Kenya; Green Hills Hotel, Nyeri, Kenya, 3rd June-6th June 1991

, 1991
Abdullah, Mohamed, Oduwo, R.N., Katsivo, M.N.   +2 more
core   +1 more source

Six Essential Oils as Potential Antibacterial Agents Against Extensively Drug-Resistant (XDR) Gram-Negative Clinical Isolates. [PDF]

Antibiotics (Basel)
Bǎdescu-Chircea B, Liga S, Licker M, Dugăeşescu D, Popa MD, Piluţ CN, Vulpie S, Buda VO, Muntean D.   +8 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The evidence-informed decision-making process of the National Essential Medicines List Committee and Essential Drugs Programme

Journal of the Colleges of Medicine of South Africa
Amanda Brewer, Janine Jugathpal, Kim MacQuilkan, Marc Blockman, Andrew Gray, Tamara Kredo, Reneé de Waal, Lesley Robertson   +7 more
doaj   +1 more source

EEG-Based Neurophysiological Assessment of Pharmacopoeial-Quality Essential Oils and Development of Stable Micro-Emulsion Systems for Aromatherapy Applications. [PDF]

Pharmaceuticals (Basel)
Karaaslan M, İleri Özler HK, Ergene B, Biltekin Kaleli SN, Üstündağ Okur N, Aykan S, Saltan İşcan HG.   +6 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Essential Oil Composition and Biological Activities of <i>Hyptis eriocephala</i>, an Aromatic Lamiaceae Species from Southern Ecuador. [PDF]

Plants (Basel)
Guaya D, Hernández AC, Morocho V.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Comprehensive improvement of induced ruminal acidosis in lambs: targeted microencapsulated essential oils and marine algae restore rumen function, systemic health, immunity, and welfare. [PDF]

Front Vet Sci
Kishawy ATY, Metwally E, Pet I, Attia GA, Ahmed FA, Saed H, Moharam H, Mohammed AS, Ahmadi M, Dumitrescu G, Helal ZF, Abdelfattah-Hassan A, Abdel-Raheem SM, Ibrahim D.   +13 more
europepmc   +1 more source