Results 1 to 10 of about 22,958 (212)

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link? [PDF]

Mov Disord Clin Pract
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Jurado E, Bavdhankar K, Garg D, Magrinelli F, Morris H, Bhatia K.   +5 more
europepmc   +2 more sources

Ruxolitinib reverses systemic vasculitis driven by JAK2 V617F–mutated essential thrombocythemia: a case report [PDF]

Frontiers in Immunology
BackgroundVasculitis associated with myeloproliferative neoplasms is rare, and reports on its treatment are limited. Herein, we report a case of Janus Kinase2 (JAK2) V617F mutation–positive essential thrombocythemia (ET) associated with vasculitis.Case ...
Yutaro Ashida, Shinji Ota, Nao Ishidoya, Yasuhisa Murai, Kyoko Amenomori, Keisuke Hasui, Shogo Kawaguchi, Satoko Yamaguchi, Hiroto Hiraga, Kosuke Kamata, Hiroaki Ichikawa, Hirofumi Tomita, Zaiqiang Yu, Masahito Minakawa, Hirotake Sakuraba   +14 more
doaj   +2 more sources

Clinical and hematological profile of patients with philadelphia-negative myeloproliferative neoplasms: First report from the Ecuadorian registry [PDF]

Hematology, Transfusion and Cell Therapy
Introduction: Philadelphia-negative myeloproliferative neoplasms are clonal blood disorders characterized by abnormal blood cell production. This study explores the clinical and epidemiological profiles of 111 Ecuadorian patients diagnosed with ...
C Freire, A Noboa, G Acosta, C León, H Chiang-Wong, M Buenaño, R Loachamin, P Santana, F Huamán-Garaicoa   +8 more
doaj   +2 more sources

Allele burden expansion in <i>JAK2</i> ^V617F and <i>CALR</i>-mutated myeloproliferative neoplasms predicts disease progression and is associated with anagrelide treatment. [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 9, September 2026.
Ng ZY, Cottin L, Demoy M, Paz DL, Orvain C, Lambert WC, Ianotto JC, Lippert E, Ross DM, Iarossi D, Khan A, Lock D, Truong C, Laribi K, Yang YF, Gagnon LL, Ugo V, Harrison CN, O'Sullivan J.   +18 more
europepmc   +2 more sources

Thrombotic and hemorrhagic events in 2016 World Health Organization-defined Philadelphia-negative myeloproliferative neoplasm [PDF]

The Korean Journal of Internal Medicine, 2021
Background/Aims Recent changes in the diagnostic criteria for myeloproliferative neoplasms (MPNs) and increasing patient numbers necessitate updating of the data on vascular events in patients with such disorders.
Ik-Chan Song, Sang Hoon Yeon, Myung-Won Lee, Hyewon Ryu, Hyo-Jin Lee, Hwan-Jung Yun, Seon Young Kim, Deog-Yeon Jo   +7 more
doaj   +1 more source

Unpredictable post-laparoscopic bleeding in essential thrombocytosis: a call for additional safety measures [PDF]

Journal of Medicine and Life Science, 2023
Patients with essential thrombocythemia (ET) can undergo laparoscopy without international precautions. This case report describes an ET with a mild increase in the platelet count that developed after laparoscopic surgery and prolonged intraperitoneal ...
Atef M.M. Darwish, Dina A.M. Darwish, Yasser Abdelaal   +2 more
doaj   +1 more source

Management of thrombocythemia [PDF]

F1000Research, 2014
Essential thrombocythemia is a clonal myeloproliferative neoplasm characterized by an elevated platelet count, the potential for both microvascular and macrovascular sequelae, and a risk for transformation to myelofibrosis or acute myeloid leukemia.
Gowin, Krisstina, Mesa, Ruben
openaire   +2 more sources

Invasive ductal breast carcinoma preceded by CALR‐positive essential thrombocythemia

Clinical Case Reports, 2021
Persistent thrombocytosis in patients with cancer needs workup because it can be linked to essential thrombocytosis. The management should be individualized to start treatment for low‐risk essential thrombocytosis due to the combined risk of thrombosis.
Elrazi A. Ali, Hind Elmalik, Nabil E. Omar, Mohamed A. Yassin   +3 more
doaj   +1 more source

Essential thrombocythemia [PDF]

Orphanet Journal of Rare Diseases, 2007
Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000. The median age at diagnosis is 65 to 70 years, but the disease may occur at any age.
openaire   +5 more sources

Spontaneous bacterial peritonitis complicating extensive splanchnic vein thrombosis, a rare manifestation of essential thrombocythemia: A case report

Clinical Case Reports, 2023
Key Clinical Message Clinicians should be mindful of the rare occurrence of spontaneous bacterial peritonitis in essential thrombocythemia with extensive splanchnic vein thrombosis, especially when patients with ascites exhibit fever and abdominal pain ...
Saurav Agrawal, Sandesh Rayamajhi, Aadesh Rayamajhi, Susmin Karki, Anand Deo, Kirti Kala Kharel, Manoj Lamsal, Rabin Hamal   +7 more
doaj   +1 more source