Results 21 to 30 of about 22,958 (212)

Genetic studies of hereditary thrombocythemia [PDF]

, 2013
Hereditary thrombocythemia (HT) is a familial myeloproliferative disorder characterized by an elevated platelet count in peripheral blood. Thrombocytosis is due to a genetic alteration that can be transmitted to the offspring.
Pianta, Annalisa
core   +1 more source

Does Reactive Thrombocytosis Observed in Iron Deficiency Anemia Affect Plasma Viscosity?

Turkish Journal of Hematology, 2012
OBJECTIVE: The accompanying thrombocytosis is referred to as the major factor associated with thromboembolism in iron deficiency anemia (IDA). Increased viscosity may increase the risk of thrombosis.
Selami K. Toprak, İbrahim Tek, Sema Karakuş, Nihat Gök, Nazmiye Kurşun   +4 more
doaj   +1 more source

Studies of JAK2 mutations in myeloproliferative disorders [PDF]

, 2008
Myeloproliferative disorders (MPD) are diseases characterized by clonal hematopoiesis with overprodution of mature cells from erythroid, megakaryocytic and myeloid lineages.
Li, Sai
core   +1 more source

Essential thrombocythemia [PDF]

, 1998
Review on Essential thrombocythemia, with data on clinics, and the genes ...
Huret, JL
core   +1 more source

Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia

Background: We conducted a randomized comparison of hydroxyurea with anagrelide in the treatment of essential thrombocythemia. Methods: A total of 809 patients with essential thrombocythemia who were at high risk for vascular events received low-dose ...
Revell P, for the United Kingdom Medical Research Council Primary Thrombocythemia 1 Study, Reilly JT, Campbell PJ, Wilkins BS, Bareford D, Woodcock BE, Wheatley K, Grigg AP, East CL, Harrison CN, van der Walt JD, Green AR, Buck G   +13 more
core   +5 more sources

Retinal neovascularization in the setting of -mutation positive essential thrombocythemia

SAGE Open Medical Case Reports, 2023
Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger, Marwan R Abdulaal, Angeline L Wang   +2 more
doaj   +1 more source

Thromboembolic complication in Essential Thrombocythemia

The Pan African Medical Journal, 2012
The presenting symptoms of patients with essntial thrombocythemia are quite variable. After detection of thrombocytosis about 13 to 37 percent of patients relate symptoms due to hemorrhagic event, and about 22 to 84 percent of patients report ...
Zahra Mozaheb
doaj   +1 more source

Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy

Haematologica, 2008
We analyzed the effect of hydroxyurea on the JAK2V617F allelic ratio (%JAK2V617F), measured in purified blood granulocytes, of patients with polycythemia vera and essential thrombocythemia.
François Girodon, Céline Schaeffer, Cédric Cleyrat, Morgane Mounier, Ingrid Lafont, Frédéric Dos Santos, Aurélie Vidal, Marc Maynadié, Sylvie Hermouet   +8 more
doaj   +1 more source

Thrombospondin in essential thrombocythemia [PDF]

Blood, 1986
Abstract Essential thrombocythemia is a myeloproliferative disorder characterized by frequent bleeding and thrombotic complications. On a molecular level, two abnormalities of platelet thrombospondin have been identified: abnormal glycosylation of the intact 185,000-dalton chain has been detected and a shortened form of the ...
J, Lawler, A M, Cohen, F C, Chao, D J, Moriarty   +3 more
openaire   +3 more sources

A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family

Haematologica, 2008
Background Hereditary thrombocythemia is an autosomal dominant disorder with clinical features resembling sporadic essential thrombocythemia.
Kun Liu, Robert Kralovics, Zbigniew Rudzki, Barbara Grabowska, Andreas S. Buser, Damla Olcaydu, Heinz Gisslinger, Ralph Tiedt, Patricia Frank, Krzysztof Okoñ, Anthonie P.C. van der Maas, Radek C. Skoda   +11 more
doaj   +1 more source