Results 11 to 20 of about 22,958 (212)
Essential thrombocythemia: a rare disease in childhood
Revista Brasileira de Hematologia e Hemoterapia, 2013 Essential thrombocythemia is an acquired myeloproliferative disorder characterized by the proliferation of megakaryocytes in bone marrow, leading to a persistent increase in the number of circulating platelets and thus increasing the risk for thrombotic ...
Julia Maimone Beatrice +1 more
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Systemic Mastocytosis and Essential Thrombocythemia: Case Report and Literature Overview [PDF]
Medicina, 2019 Mastocytosis is a rare disease in which heightened amounts of mast cells accumulate in the skin, bone marrow, and other visceral organs. Upon activation, mast cells release a wide variety of preformed or newly synthesized mediators which can induce ...
Mauro Cancian +6 more
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Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations [PDF]
Haematologica, 2015 The JAK2 V617F mutation, the thrombopoietin receptor MPL W515K/L mutation and calreticulin (CALR) mutations are mutually exclusive in essential thrombocythemia and support a novel molecular categorization of essential thrombocythemia.
Carla Al Assaf +12 more
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Acute megakaryoblastic transformation from essential thrombocythemia
Human Pathology: Case Reports, 2017 Essential thrombocythemia (ET) is a Philadelphia chromosome-negative myeloproliferative neoplasm characterized by sustained thrombocytosis. Its transformation into acute leukemia is a rare event (5% at 20 years).
Tariq M. Roshan +3 more
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BCR/ABL positive thrombocythemia: a diagnostic dilemma
The Egyptian Journal of Internal Medicine, 2017 Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients.
Lubna Zafar +3 more
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The role of oxidative stress in essential thrombocythemia [PDF]
Archives of the Balkan Medical Union, 2018 In patients with myeloproliferative neoplasms (MPNs), including essential thrombocythemia, current studies have demonstrated a JAK2V617F-dependent reactive oxygen species (ROS) elevation partially mediated by a decrease in catalase expression associated ...
Cornel Moisă +6 more
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Diagnosis and Management of Essential Thrombocythemia: A Comprehensive Review [PDF]
Documenta HaematologicaMyeloproliferative neoplasms, including essential thrombocythemia, are characterized by clonal proliferations of hematopoietic stem cells, leading to an increase in mature myeloid lineage cells.
Sandra LAZAR +6 more
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Papel de la activación leucocitaria y plaquetaria en la trombosis de los síndromes mieloproliferativos crónicos [PDF]
, 2008 [spa] INTRODUCCIÓN Y OBJETIVOS: La causa fundamental de la trombosis en la policitemia vera y la trombocitemia esencial es el aumento de la viscosidad sanguínea secundaria a la eritrocitosis así como el incremento del número de plaquetas y las ...
Álvarez Larrán, Alberto
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Journal of Nepal Medical Association, 2022 Introduction: Essential thrombocythemia, a myeloproliferative condition with an increased number of circulating platelets, is a rare hematological malignancy. The aim of the study is to find out the prevalence of essential thrombocythemia among patients
Sanjit Kumar Sah +9 more
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THPO-MPL pathway and bone marrow failure
Hematology/Oncology and Stem Cell Therapy, 2015 Single or multilineage bone marrow failure can be a serious health problem caused by hereditary and non-hereditary causes such as exposure to drugs or environmental toxins.
Majed Dasouki, Irfan Saadi, Syed O Ahmed
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