HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
The influence of exogenous cholesterol on hepatic lipid composition of the rat*
Journal of Lipid Research, 1962 Rats were fed diets containing cottonseed oil and/or cholesterol, cholic acid, methyl esters of long-chain fatty acids, and tocopherol. Livers, hearts, and aortas were examined histologically; liver lipids were fractionated by silicic acid chromatography;
Robert J. Morin +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
wiley +1 more source
CHANGES IN PLASMA LIPID COMPOSITION IN PATIENTS WITH ESSENTIAL HYPERTENSION
Российский кардиологический журнал, 2003 To examine the relation between serum fatty acids, blood pressure and heart failure in hypertensive patients we conducted a study of 58 patients with essential hypertension (mean age 45,1 ± 9,4 years) and 22 healthy subjects.
A. V. Govorin +3 more
doaj
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Nutrition & Metabolism, 2012 Background The vitamin-like omega-3 and omega-6 essential fatty acids are converted in the body to a large family of hormones which act at selective receptors that occur on nearly every cell and tissue.
Lands Bill, Lamoreaux Etienne
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Short communication: The comparison of fatty acids, fat-soluble vitamins and cholesterol in the muscle of wild caught, cage and pond reared rainbow trout (Oncorhynchus mykiss W., 1792) [PDF]
, 2017 Fish meat is a good source of fats, proteins, vitamins and minerals. Therefore, it is an important component of a balanced diet for humans (Stancheva et al., 2010). Fish store the lipids in various organs, particularly in muscles and liver.
Parlak, A.E., Ural, M.S., Çalta, M.
core
The risk of essential fatty acid insufficiency in patients with inflammatory bowel diseases: fatty acid profile of phospholipids in serum and in colon biopsy specimen [PDF]
, 2022 Jolanta Bugajska +3 more
openalex +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Nutritional profile of phytococktail from trans-Himalayan plants.
PLoS ONE, 2013 We estimated the nutritive value, vitamin content, amino acid composition, fatty acid content, and mineral profile of a phytococktail comprising sea buckthorn (Hippophae rhamnoides), apricot (Prunus armeniaca), and roseroot (Rhodiola imbricata) from ...
Priyanka Dhar +5 more
doaj +1 more source