Results 101 to 110 of about 1,901,618 (330)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Aggregates safeguarding map of Mid Wales (South) [PDF]

open access: yes, 2012
Aggregates Safeguarding Map of Wales - As mineral resources are finite and are not evenly distributed, knowledge about their whereabouts is essential for making effective and sustainable planning decisions that consider the needs of future generations ...

core  

Linear maps preserving the essential spectral radius

open access: yesLinear Algebra and its Applications, 2008
AbstractLet L(H) be the algebra of all bounded linear operators on an infinite dimensional complex Hilbert H. We characterize linear maps from L(H) onto itself that preserve the essential spectral radius.
M. Sarih   +2 more
openaire   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

On essential spectra of operator-matrices and their Feshbach maps

open access: yesJournal of Mathematical Analysis and Applications, 2004
The paper under review deals with spectral properties of block operator matrices on a direct sum of Banach spaces. The investigated problems are important because many complicated boundary value problems and systems of differential equations can be written in this form.
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

A Method of Cartographic Visualization for Climate Change Maps

open access: yesKartografija i Geoinformacije, 2011
Maps are essential in climate change research. This paper considers examples of cartographic visualizations for different climate change characteristics. International map symbol systems used in climate change maps are analyzed.
Nadka Stoimenova
doaj  

Uncertainty maps for model-based global climate classification systems

open access: yesScientific Data
Climate classification systems (CCSs) are emerging as essential tools in climate change science for mitigation and adaptation. However, their limitations are often misunderstood by non-specialists.
Andrés Navarro   +3 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

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