Results 51 to 60 of about 706,087 (286)

Chemical composition and antibacterial activity from essential oil of Artemisia sieberi Besser subsp. Sieberi in North of Iran

, 2007
The chemical composition and antibacterial effect of Artemisia siberi essential oil were studied in this research. The composition of essential oil from aerial parts was analyzed by GC/MS and its antibacterial effect were determined by disc diffusion ...
Ahmadi, A.R., Bakhshandeh Nosrat, S., Behmanesh, B., Ghaemi, E.O., Heshmati, G.A., Mazandarani, M., Rezaei, M.B.   +6 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Comparitive Study on Essential Oil in Natural and In vitro Regenerated Plants of Vetiveria zizanioides (Linn.) Nash [PDF]

, 2011
In vitro studies with rhizome explants of Vetiveria zizanioides obtained through organogenetic pathway was focused on the difference in essential oil content with that of control plants. There was variation exhibited by In vitro regenerated
Jayalakshmi, N.R., Shiva Kameshwari, M.N., Thara Saraswathi, K.J., Vyshali, P.   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Constituintes químicos voláteis das folhas e galhos de Zanthoxylum syncarpum Tull. Volatile chemical constituents of the leaves and twigs from Zanthoxylum syncarpum Tull.

Química Nova, 2009
The essential oils of the leaves and twigs from Zanthoxylum syncarpum Tull. were examined by GC/MS and GC-FID. Variation in the oil composition relative to the harvesting time was also described.
Mariano George Sousa Vieira, João Vito Barroso de Freitas, Manoel Nelson de Lima Neto, Nilce Viana Gramosa, Edson Paula Nunes   +4 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Chemical composition and antimicrobial activities of the essential oil from Myrtus communis leaves [PDF]

, 2013
: Nosocomial pathogens are associated with increased hospital stay lengths and mortality rates. Increasing resistance to antibiotics makes the treatment of these infections more difficult.
Abbasi, Nadia., Bandegani, Azadeh, Bazargani, Abdollah., Ghasemi, Younes., Lorigooini, Zahra., Mirzamohammadi, Solmaz., Moein, Mahmoodreza., Pakshir, Keyvan., Rahimi, Mohammad Javad., Zomorodian, Kamiar.   +9 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Harvest time on the content and chemical composition of essential oil from leaves of guava

Ciência Rural
: The essential oil plants contents can be affected by several factors. For example, in certain plants, collection time has been observed to affect the content and chemical composition of the essential oil obtained from the plant.
Elizabeth Aparecida Josefi da Silva, Vanessa Paula da Silva, Cassia Cristina Fernandes Alves, José Milton Alves, Edson Luiz Souchie, Luiz Cláudio de Almeida Barbosa   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source