Results 41 to 50 of about 109,906 (296)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Physicochemical parameters and antioxidant activity of summer savory essential oil (Satureja hortensis L.) [PDF]

BIO Web of Conferences
Summer savory (Satureja hortensis L.), Lamiaceae family, was used in folk medicine and food industry, and the resulting essential oil was used to flavor various food products, as well as a biologically active substance in cosmetics.
Gandova Vanya, Lazarov Anton, Petkova Nadezhda, Stoyanova Albena   +3 more
doaj   +1 more source

The Essential Oil of Ginger [PDF]

Scientific American, 1881
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openaire   +2 more sources

Analgesic Potential of Essential Oils [PDF]

Molecules, 2015
Pain is an unpleasant sensation associated with a wide range of injuries and diseases, and affects approximately 20% of adults in the world. The discovery of new and more effective drugs that can relieve pain is an important research goal in both the pharmaceutical industry and academia.
José F. Sarmento-Neto, Cícero Francisco Bezerra Felipe, Lázaro Gomes do Nascimento, Damião Pergentino de Sousa   +3 more
openaire   +4 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Essential oils [PDF]

Zeitschrift für Naturforschung C, 2020
Muttalib, Al-Shalah, Lubna Abdul, Khazal, Kadhim Hindi, Nada, Harjan, Mohsen, Israa   +2 more
openaire   +5 more sources

Technological and sensory characteristics of honey based candy [PDF]

BIO Web of Conferences
The aim of the present work was to investigate the possibilities of sugar replacing with honey in candies processing. Four candy samples were examined. Honey based groups - 10% (M10), 15% (M15) and 20% (M20) honey and sugar substitute - isomalt, compared
Yankova-Nikolova Anastasia, Hadjikinova Raina, Opalchenova Gabriela, Vlahova-Vangelova Desislava   +3 more
doaj   +1 more source

Lupinus angustifolius L. cultivar “Boregine” from South of Bulgaria: a source of nutrients and natural biologically active components☆

Oilseeds and fats, crops and lipids, 2022
Nowadays, the requirements of new sources of natural food components are constantly expanding worldwide. On one hand, the constituents derived from the common agriculture plants satisfy the needs of the body to function properly.
Petkova Zhana, Antova Ginka, Angelova-Romova Maria, Todorova Ilinka, Stoyanova Magdalena, Stoyanova Albena   +5 more
doaj   +1 more source

Essential Oils and COVID-19

Molecules, 2022
Herbal products are a major source of herbal medicines and other medicines. Essential oils have shown various pharmacological activities, such as antiviral activity, and therefore are proposed to have potential activity against SARS-CoV-2. Due to their lipophilicity, essential oils can easily penetrate the viral membrane and cause the viral membrane to
Mahmoud Fahmi Elsebai, Marzough Aziz Albalawi   +1 more
openaire   +3 more sources