Results 51 to 60 of about 6,803 (208)

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

, 2020
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U., Eichele, G., Hempel, K., Jessberger, R., Kühnel, A., McNicoll, F., Whelan, G.   +6 more
core   +1 more source

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time [PDF]

, 2006
Peer ...
Andrulis ED, Anne D Donaldson, Askree SH, Bermudez VP, Boulton SJ, Bowman GD, Bylund GO, Bystricky K, Cosgrove AJ, Dimitrova DS, Donaldson AD, E Douglas Robertson, Ferguson BM, Gartenberg MR, Gilbert DM, Gilbert N, Gotta M, Gottschling DE, Gravel S, Hanna JS, Hayashi A, Hediger F, Heun P, Heun P, Kenna MA, Kim J, Laroche T, Martin SG, Mayer ML, Merkle CJ, Naiki T, Ohta S, Palladino F, Petronczki M, Porter SE, Raghuraman MK, Raghuraman MK, Roy R, Shin-ichiro Hiraga, Skibbens RV, Smolikov S, Stellwagen AE, Stevenson JB, Strahl-Bolsinger S, Straight AF, Suter B, Taddei A, Taddei A, Tanabe H, Tanaka T, Tham WH, Woodfine K   +51 more
core   +2 more sources

Condensin I protects meiotic cohesin from WAPL-1 mediated removal. [PDF]

PLoS Genetics, 2018
Condensin complexes are key determinants of higher-order chromatin structure and are required for mitotic and meiotic chromosome compaction and segregation.
Margarita R Hernandez, Michael B Davis, Jianhao Jiang, Elizabeth A Brouhard, Aaron F Severson, Györgyi Csankovszki   +5 more
doaj   +1 more source

Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex? [PDF]

, 2013
This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.Peer ...
Donaldson, Anne D, Kubota, Takashi, Myung, Jae-Kyung   +2 more
core   +1 more source

Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

eLife, 2020
Sister chromatid cohesion essential for mitotic chromosome segregation is thought to involve the co-entrapment of sister DNAs within cohesin rings. Although cohesin can load onto chromosomes throughout the cell cycle, it only builds cohesion during S ...
Madhusudhan Srinivasan, Marco Fumasoni, Naomi J Petela, Andrew Murray, Kim A Nasmyth   +4 more
doaj   +1 more source

Arabidopsis thaliana WAPL is essential for the prophase removal of cohesin during meiosis. [PDF]

PLoS Genetics, 2014
Sister chromatid cohesion, which is mediated by the cohesin complex, is essential for the proper segregation of chromosomes in mitosis and meiosis.
Kuntal De, Lauren Sterle, Laura Krueger, Xiaohui Yang, Christopher A Makaroff   +4 more
doaj   +1 more source

Meiotic Cohesin and Variants Associated With Human Reproductive Aging and Disease

Frontiers in Cell and Developmental Biology, 2021
Successful human reproduction relies on the well-orchestrated development of competent gametes through the process of meiosis. The loading of cohesin, a multi-protein complex, is a key event in the initiation of mammalian meiosis. Establishment of sister
Rachel Beverley, Meredith L. Snook, Miguel Angel Brieño-Enríquez   +2 more
doaj   +1 more source

Cohesin causes replicative DNA damage by trapping DNA topological stress [PDF]

, 2020
DNA topological stress inhibits DNA replication fork (RF) progression and contributes to DNA replication stress. In Saccharomyces cerevisiae, we demonstrate that centromeric DNA and the rDNA array are especially vulnerable to DNA topological stress ...
Baxter, Jonathan, Keszthelyi, Andrea, Minchell, Nicola Elizabeth   +2 more
core   +1 more source

Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast.

PLoS ONE, 2010
Multiple genome maintenance processes are coordinated at the replication fork to preserve genomic integrity. How eukaryotic cells accomplish such a coordination is unknown.
Jordan B Rapp, Chiaki Noguchi, Mukund M Das, Lisa K Wong, Alison B Ansbach, Allyson M Holmes, Benoit Arcangioli, Eishi Noguchi   +7 more
doaj   +1 more source

The Role of Structural Maintenance of Chromosomes Complexes in Meiosis and Genome Maintenance: Translating Biomedical and Model Plant Research Into Crop Breeding Opportunities

Frontiers in Plant Science, 2021
Cohesin is a multi-unit protein complex from the structural maintenance of chromosomes (SMC) family, required for holding sister chromatids together during mitosis and meiosis.
Pablo Bolaños-Villegas, Pablo Bolaños-Villegas   +1 more
doaj   +1 more source