Results 91 to 100 of about 381,897 (302)
MIGRACIÓN MÉXICO-ESTADOS UNIDOS: PARADOJA LIBERAL RENOVADA DEL TLCAN
Problemas del Desarrollo, 2015 RESUMENEl objetivo de esta investigación es presentar algunas de las reflexiones más importantes sobre los signos y las repercusiones teóricas y empíricas que en cuanto a la migración de mexicanos hacia Estados Unidos han resultado tras los 20 años del Tratado de Libre Comercio de América del Norte (tlcan).
openaire +4 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
El debate de Neumann con el marxismo [PDF]
, 2019 In his research on The Governance of the Rule of Law (1936), Franz L. Neumann (1900-1954) claims that nineteenth century liberal capitalism had transformed into an Era of monopolistic capitalism in the twentieth century.
Sassmannshausen, Felix
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
OS MODELOS DE ESTADO E AS CARACTERÍSTICAS DA JURISDIÇÃO A
Revista Eletrônica do Curso de Direito da UFSM, 2008 O Estado Moderno, diferentemente das formas pré-modernas de organização, é caracterizado pela dominação burocrática. Apresentou-se inicialmente como Estado Absoluto, em face do qual se opôs o Estado Liberal e, posteriormente o Estado Social.
Ana Luísa Zago de Moraes
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The New Developmentalism and Conventional Orthodoxy [PDF]
O Fracasso das Políticas e Reformas Propostas por Washington e Nova York, Aqui Denominadas Ortodoxia Convencional , em Promover a Estabilização e o Crescimento Econômico na América Latina Abriu Espaço para o Surgimento de uma Estratégia Nacional de ...
Pereira, Luiz Carlos Bresser
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Revista Espiga, 2007 El escrito gira en torno tanto a la campaña militar de 1856-°©‐‑ 57, como también de la figura del héroe nacional Juan Santamaría, como eje primordial de la creación artística al servicio de la invención civilista proyectada por los “padres” del Estado ...
Verónica Urroz Leal
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source