Results 111 to 120 of about 381,853 (304)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

CÓDIGOS DECIMONÓNICOS Y DERECHOS FUNDAMENTALES

open access: yesTeoría & Derecho, 2020
El problema de la relación entre Códigos y Derechos Fundamentales puede ser visto a la luz de la llamada «constitución material» El Código es complemento de la Constitución material liberal: se puede hablar de la existencia de un par funcional ...
Ángel M. López y López
doaj  

Liberalismo, derechos humanos y desarrollo en un orden político democrático [PDF]

open access: yes, 2014
El objetivo del presente documento plantea que al garantizar los derechos humanos se crean condiciones para el florecimiento de la ciudadanía, misma que es indispensable para fomentar el desarrollo de una nación con un Estado democrático de derecho.
ESPEJEL MENA, JAIME   +3 more
core  

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Ideologia liberal e construção do Estado do Brasil

open access: yesAnais do Museu Paulista: História e Cultura Material, 1981
This paper inquires into the limits of the actuation of the principies of North-American liberalism in the process of building up the Brazilian State during the last century. These principies are opposed to the pressures exercised by forces of the counter-revolutionary ideology, among them the “haitinism”, a term used to convey the increasing dread of ...
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Guerra y Paz en el Siglo XXI [PDF]

open access: yes, 2011
En “Guerra y Paz en el Siglo XXI”, Eric Hobsbawm desarrolla una selección de penetrantes conferencias, en las cuales ensaya una aguda crítica al imperialismo y la globalización.
Álvarez Polanco, Alejandro
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

La educación moral como asunto público [PDF]

open access: yes, 2006
Este artículo presenta un planteamiento para la comprensión y el análisis político de la educación moral en México. Partiendo de que la sociedad mexicana está viviendo un proceso de transición en el que las expectativas sociales y económicas sobre la ...
Barba Casillas, Bonifacio
core   +1 more source

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