Endogenous pathway dysregulation in Kluyveromyces marxianus under nitrogen limitation drives 2-phenylethyl acetate and 2-phenylethanol overproduction. [PDF]
González-Lozano KJ +5 more
europepmc +1 more source
NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang +5 more
wiley +1 more source
[Colonial collections at the Universidade de Lisboa: criteria for characterizing sensitive heritage]. [PDF]
Simões C, Mateus C, Godinho A.
europepmc +1 more source
Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
Recrudescence of tuberculosis in the state of São Paulo post-COVID-19: trends and clusters. [PDF]
Tavares RBV +13 more
europepmc +1 more source
A sedução das armas. Radicalização na contestação ao Estado Novo [PDF]
Ferreira, Ana Sofia
core +1 more source
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Draft genome sequences of <i>Bacillus velezensis</i> and <i>Bacillus subtilis</i> strains with plant growth-promoting and drought resilience potential. [PDF]
Silva Ferreira LV +4 more
europepmc +1 more source
Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman +3 more
wiley +1 more source

