Results 201 to 210 of about 1,021,196 (293)

<i>De <i>N</i>ovo</i>-Designed Miniprotein Inhibits the Enzymatic Activity of the SARS-CoV-2 Main Protease. [PDF]

J Chem Inf Model
Lima TE, Moreira EG, Coêlho DF, Cruz CHB, Dhalia R, Leite BHS, Xavier LS, Illana MP, Wallau GL, Viana IFT, Lins RD.   +10 more
europepmc   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Brazilian consensus- and evidence-based recommendations in the diagnosis and treatment of pancreatic exocrine insufficiency in patients after digestive surgeries. Position paper of six brazilian medical societies of surgery. [PDF]

Arq Bras Cir Dig
Montagnini AL, Bernardo WM, Kassab P, Quireze Junior C, Oliveira CVC, Diniz AL, Pinheiro RN, Oliveira AF, Portari Filho P, Ravanini GAG, Forones NM, Pertille MFK, Valezi AC, Dantas ACB, Marzinotto MAN, Figueira ER, Jukemura J, Ribeiro Junior U, Herman P.   +18 more
europepmc   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

The Role of the Naples Prognostic Score in the Evaluation of SVG Patency Following CABG Surgery. [PDF]

Arq Bras Cardiol
Gürsoy MO, Güneş H.
europepmc   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Study of Nutrition, Health, and Food Security of Indigenous Peoples in the State of Alagoas, Brazil (ENSSAIA): Methodological Aspects. [PDF]

Food Sci Nutr
Dos Santos TR, de Oliveira VC, Cardoso MA, de Assunção ML, da Silva AH, Vieira RCDS, Barbosa LB, Maynart WHDC, Dos Santos EA, Ferreira HDS.   +9 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Transcriptomic, proteomic and biochemical comparison of luminescent and non-luminescent Keroplatinae larvae (Diptera: Keroplatidae). [PDF]

Insect Mol Biol
Silva JR, Pelentir GF, Amaral DT, Stevani C, Viviani VR.   +4 more
europepmc   +1 more source

A sedução das armas. Radicalização na contestação ao Estado Novo [PDF]

, 2016
Ferreira, Ana Sofia
core   +1 more source