Results 171 to 180 of about 39,453 (284)

The purification of choline-esterase [PDF]

Biochemical Journal, 1935
E, Stedman, E, Stedman
openaire   +2 more sources

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

Distribution and Evolutionary Signatures of a Broad-Spectrum Pesticide-Degrading Carboxylesterase TriS From Strain S113. [PDF]

Environ Microbiol
Tian Y, Lai L, Wang W, Ma Y, Huang X.
europepmc   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

Comparison of serum paraoxonase 1, butyrylcholinesterase, and carboxylesterase activities among dogs, cats, micro-mini pigs, and goats. [PDF]

J Vet Med Sci
Doi S, Kobayashi Y, Takashima S, Ide W, Murahata Y, Yayota M, Takasu M, Sassa-O'Brien Y, Shibata S.   +8 more
europepmc   +1 more source

Repurposed catechol‐O‐methyltransferase inhibitors tolcapone and entacapone preferentially suppress aggregation and seeding of P301 mutant tau in human neuronal models

British Journal of Pharmacology, EarlyView.
Background and purpose Pathogenic aggregation and propagation of seed‐competent TAU assemblies drive tauopathies. MAPT P301 mutations accelerate aggregation and enhance seed competence, yet pharmacological strategies selectively targeting these pathogenic species remain limited.
Ihor Kozlov, Yu‐Sheng Hung, Sudeep Roy, Alladi Charanraj Goud, Roman Kouřil, Yu‐Hui Wong, Viswanath Das   +6 more
wiley   +1 more source

Heterologous expression of a cold-active small esterolytic enzyme from <i>Pseudomonas sivasensis</i> R11S16 and its potential for azithromycin removal. [PDF]

3 Biotech
Çon G, Karakaya E, Saygin H, Saricaoğlu S, Könen Adıgüzel S, Adıgüzel AO.   +5 more
europepmc   +1 more source

EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect

Cancer Science, EarlyView.
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu, Jingjia Chang, Zhiyong Li, Jin Wu, Pengfei Yu, Jingjing Zheng, Li Li, Jia Tao, Hao Wu, Yintao Li, Ming Liu   +10 more
wiley   +1 more source

Acinetobacter guillouiae, a lipolytic strain isolated from sludge capable of partially depolymerising polyethylene terephthalate: genomic, proteomic, and biochemical insights. [PDF]

BMC Microbiol
Akhtar N, Najjari A, Magnone A, Yerebakan EC, Bernfur K, Tullberg C, Awan MS, Majeed Z, Grey C, Zhang B, Linares-Pastén JA.   +10 more
europepmc   +1 more source

Mesenchymal stromal cell‐derived extracellular vesicles improve islet β‐cell metabolic function via miRNA‐mediated regulation of Ankyrin‐B expression

Diabetic Medicine, EarlyView.
Abstract Aims Mesenchymal stromal‐cell‐derived extracellular vesicles (MSC‐EVs) improve islet function, which may be mediated in part through the delivery of microRNAs (miRNAs) to β‐cells. To investigate the underlying mechanisms, we identified the most abundant MSC‐EV miRNAs, their relative transfer to β‐cells and the extent to which Ankyrin‐B (Ank2 ...
Tzu‐Wen Hong, Ryea Arora, Rosie Sullivan, Zekun Lyu, William T. Blackstone Whines, Lydia F. Daniels Gatward, Ella L. Hubber, Tien‐Chi Huang, Aileen J. F. King, Shanta J. Persaud, Peter M. Jones   +10 more
wiley   +1 more source