Garadacimab for the long‐term prophylaxis of hereditary angioedema
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün +5 more
wiley +1 more source
Whole-genome sequence dataset of <i>Pasteurella multocida</i> strain EH32 isolated from buffaloes in Vietnam. [PDF]
Van Nguyen T +6 more
europepmc +1 more source
Pharmacokinetics of Subcutaneous C1 Esterase Inhibitor (human) with Recombinant Human Hyaluronidase for the Prevention of Angioedema Attacks in Patients with Hereditary Angioedema [PDF]
William R. Lumry +9 more
openalex +1 more source
Abstract This study evaluated whether adjunctive 10‐methacryloyloxydecyl dihydrogen phosphate (MDP) primers enhance the microtensile bond strength (µTBS) of two universal adhesives (UAs) to dentin under artificial aging and repeated salivary contamination applied at each bonding step.
Marjorie Zanini +3 more
wiley +1 more source
Unveiling a catalytically promiscuous feruloyl esterase from Clostridium acetobutylicum. [PDF]
Li S +7 more
europepmc +1 more source
Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys
Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno +6 more
wiley +1 more source
Multi-layered metabolic remodeling of <i>Pseudomonas putida</i> for efficient conversion of lignocellulosic sugars to the precursors of advanced aviation fuel. [PDF]
Kang CW +7 more
europepmc +1 more source
Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova +6 more
wiley +1 more source
Catalytic His-loop flexibility drives high activity in hyperthermophilic esterase EstE1 while preserving structural stability. [PDF]
Nguyen K, Lee C.
europepmc +1 more source
Feruloyl esterases immobilization in mesoporous silica particles
Cyrielle Bonzom +3 more
openalex +1 more source

