Results 81 to 90 of about 805 (190)

Combined oral contraceptive with estetrol plus drospirenone: from pharmacokinetics to clinical applications

open access: yes, 2023
Introduction: Drospirenone/estetrol (DRSP/E4) is a combined oral contraceptive (COC) recently approved in several countries. It is composed of 15 mg of E4, a natural estrogen produced by human fetal liver throughout pregnancy, and 3 mg of DRSP, the first
Facchinetti F.   +4 more
core   +1 more source

Estetrol/Drospirenone – an Advance on CHC with Ethinyl Estradiol?

open access: yes, 2023
A contraceção hormonal combinada (CHC) é um dos métodos contracetivos mais utilizados em todo o mundo. As questões relacionadas com a segurança, particularmente o risco tromboembólico (TE), estão em permanente avaliação. A combinação estetrol/ drospirenona (E4/DRSP) é um contracetivo oral combinado (COC) eficaz, com um perfil de hemorragia estável e ...
Palma,Fátima   +4 more
openaire   +2 more sources

Estudio de los efectos del estetrol sobre líneas celulares y un modelo in vivo de endometriosis

open access: yes
Tesis (Doctor en Ciencias Biológicas con mención en Ciencias Fisiológicas)--Pontificia Universidad Católica de Chile, 2025El estetrol (E4) es un estrógeno natural producido principalmente por el hígado fetal humano, que ha demostrado efectos ...
Maldonado Flores, Gabriel Esteban
core   +1 more source

Impact of estetrol (E4) on hemostasis, metabolism and bone turnover in postmenopausal women

open access: yes, 2022
This study aimed to determine the effects of estetrol (E4) on hemostasis, lipids, carbohydrate metabolism and bone turnover in postmenopausal women. This study was a multicenter, randomized, double-blind placebo-controlled phase 2 trial. Participants (n =
U. Gaspard (14141100)   +15 more
core   +1 more source

Potential use of estetrol in sensorineural hearing loss protection

open access: yes, 2017
peer reviewedIntroduction and Aims: Estrogens have a positive impact on the auditory function. Indeed, estradiol (E2) treatment in animals protects against acoustic trauma and aminoglycoside toxicity and its depletion can contribute to age-related ...
LEFEBVRE, Philippe   +4 more
core  

Estetrol combined with drospirenone: an oral contraceptive with high acceptability, user satisfaction, well-being and favourable body weight control [PDF]

open access: yes, 2017
peer reviewedObjectives: This study evaluated acceptability, user satisfaction, body weight control and general well-being of estetrol (E4) combined with either drospirenone (DRSP) or levonorgestrel (LNG).
Jean-Michel Foidart   +13 more
core   +1 more source

Unconjugated estetrol in normal pregnancy.

open access: yesClinical and experimental obstetrics & gynecology, 1983
The Authors studied the levels of Estetrol (15 alpha-hydroxyestriol) in the amniotic fluid, in maternal and foetal plasma, by the RIA method, in near-term pregnancies. Higher concentrations of this steroid were found in the foetal plasma and in amniotic fluid than in the maternal plasma.
L, Benassi   +3 more
openaire   +1 more source

Estetrol attenuates neonatal hypoxic–ischemic brain injury

open access: yes, 2014
peer reviewedEstetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy by the human fetal liver. It has important antioxidative activity.
Nisolle, Michelle   +6 more
core   +1 more source

El papel del estetrol en la anticoncepción: una revisión integral

open access: yesRevista Chilena de Obstetricia y Ginecología
Esta revisión narrativa explora el papel potencial del estetrol (E4), un esteroide estrogénico natural, en la anticoncepción, analizando sus propiedades farmacológicas, su efectividad y su seguridad.
Manuel Sánchez-Prieto   +6 more
doaj   +1 more source

Estetrol/drospirenone versus 17α-ethinylestradiol/drospirenone: An extended one generation test to evaluate the endocrine disruption potential on zebrafish (Danio rerio)

open access: yesEnvironment International
Combined oral contraceptives, comprising of both an oestrogen and a progestin component, are released in aquatic environments and potentially pose a risk to aquatic wildlife by their capacity to disrupt physiological mechanisms.In this study, the ...
Sébastien Baekelandt   +9 more
doaj   +1 more source

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