Results 171 to 180 of about 279,299 (375)

Measured and estimated glomerular filtration rate. Numerous methods of measurements (Part I)

Revista de Nefrología, Diálisis y Trasplante, 2017
The loss of half the renal mass does not necessarily imply half the Glomerular Filtration Rate (GFR), meaning that there is not an exact correlation between renal mass reduction and renal function loss.
Jaime Pérez Loredo, Carlos Alberto Lavorato, Armando Luis Negri   +2 more
doaj  

Automated laboratory reporting of estimated glomerular filtration rate: is it good for the health of patients and their doctors? [PDF]

, 2007
Euan Noble, David W. Johnson
openalex   +1 more source

Microdose Cocktail Study Reveals the Activity and Key Influencing Factors of OATP1B, P‐Gp, BCRP, and CYP3A in End‐Stage Renal Disease Patients

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1303-1312, May 2025.
OATP1B, P‐gp, BCRP, and CYP3A are the most contributing drug‐metabolizing enzymes or transporters (DMETs) for commonly prescribed medication. Their activities may change in end‐stage renal disease (ESRD) patients with large inter‐individual variabilities (IIVs), leading to altered substrate drug exposure and ultimately elevated safety risk.
Weijie Kong, Yuejuan Pan, Yujie Wu, Yiyi Hu, Zhenbin Jiang, Xinkui Tian, Shuhong Bi, Song Wang, Feifei Feng, Yuyan Jin, Jiayu Li, Haiyan Li, Yue Wang, Hao Liang, Wen Tang, Dongyang Liu   +15 more
wiley   +1 more source

The impact of population-based identification of chronic kidney disease using estimated glomerular filtration rate (eGFR) reporting [PDF]

, 2007
N. Richards, Kevin Harris, Michael G. Whitfield, Dónal O’Donoghue, Ruth Lewis, M. A. Mansell, Stephen Thomas, Jonathan N. Townend, Malcolm Eames, Daniele Marcelli   +9 more
openalex   +1 more source

A Joint Pharmacometric Model of Iohexol and Creatinine Administered through a Meat Meal to Assess GFR and Renal OCT2/MATE Activity

Clinical Pharmacology &Therapeutics, EarlyView.
Accurately assessing glomerular filtration rate (GFR) from plasma creatinine concentrations is challenging in patients with unstable renal function. This study aimed to refine the understanding of creatinine kinetics for more reliable assessments of GFR and net creatinine tubular secretion (nCTS) via OCT2/MATE in humans.
Zhendong Chen, Qian Dong, Charalambos Dokos, Jana Boland, Uwe Fuhr, Max Taubert   +5 more
wiley   +1 more source

A Novel Equation to Estimate Glomerular Filtration Rate Using Beta-Trace Protein [PDF]

, 2007
Christine A. White, Ayub Akbari, Steve Doucette, Dean Fergusson, Naser Hussain, Laurent Dinh, Guido Filler, Nathalie Lepage, Greg Knoll   +8 more
openalex   +1 more source

Modeling and Simulation to Inform Apixaban Dosing in Pediatrics With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Treated With Asparaginase

Clinical Pharmacology &Therapeutics, EarlyView.
Apixaban could be a potential treatment option for the prevention of venous thromboembolism (VTE) in children with acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LL). This analysis describes an updated two‐compartment population pharmacokinetic (PPK) model that characterizes the PK variability of apixaban in pediatric patients with ALL ...
Praneeth Jarugula, Toni Ajavon‐Hartmann, Obinna Obianom, Elizabeth Ludwig, Christina Crevar, David Marchisin, Zhaoqing Wang, Weidong Chen, Bing He, Lesley G. Mitchell, Vilmarie Rodriguez, Glen Lew, Vidya Perera, Bindu Murthy, Samira Merali   +14 more
wiley   +1 more source

Urological impact of race-free estimated glomerular filtration rate equations [PDF]

International Brazilian Journal of Urology
Natália Dalsenter Avilez, José Ignacio Nolazco, Steven Lee Chang, Leonardo O. Reis   +3 more
doaj   +1 more source

Estimating Pediatric Glomerular Filtration Rates in the Era of Chronic Kidney Disease Staging

, 2005
André Mattman, Shaun Eintracht, Thomas S. Mock, Geraldine Schick, David Seccombe, R. Morrison Hurley, Colin T. White   +6 more
openalex   +1 more source

Using the modification of diet in renal disease (MDRD) and Cockcroft and Gault equations to estimate glomerular filtration rate (GFR) in older people [PDF]

, 2007
Edmund J. Lamb, Michelle C. Webb, Shelagh O’Riordan   +2 more
openalex   +1 more source