Results 71 to 80 of about 5,561,714 (285)

A Simple Estimation Scheme for Leak Detection in Pipelines [PDF]

open access: yesE3S Web of Conferences
This paper presents a simple high-gain observer to detect water leak in a pipeline system. The estimation scheme was developed based on the nonlinear model of the pipeline system.
Nguyen Thang   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Design Hybrid ARO-SVR Analysis to Predict the Pile Bearing Capacity

open access: yesJournal of Applied Science and Engineering
The assessment of the load-bearing capacity of piles holds significant importance in the design of pile foundations. This paper presents hybridized support vector regression (SVR) models by utilizing the Artificial Rabbit Optimization (ARO) and the Black
Yafan LIU, Wenjun MA
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Criticism of Standard and the Standard of Criticism [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2017
Criticism is a natural and humane phenomenon, and it originates from human’s willingness to freedom. Thought is the mental moving from the base to the result and visa-versa. So, this action is subject to evaluation and criticism.
Gholamreza Fadaie
doaj  

Hierarchical Estimator

open access: yesExpert Systems with Applications, 2011
In this paper, a new machine learning solution for function approximation is presented. It combines many simple and relatively inaccurate estimators to achieve high accuracy. It creates - in incremental manner - hierarchical, tree-like structure, adapting it to the specific problem being solved.
Brodowski, Stanisław, Podolak, Igor
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Gradient of microstructural damage along the dentato‐thalamo‐cortical tract in Friedreich ataxia

open access: yesAnnals of Clinical and Translational Neurology
Objective The dentato‐thalamo‐cortical tract (DTT) is the main cerebellar efferent pathway. Degeneration of the DTT is a core feature of Friedreich ataxia (FRDA).
Sirio Cocozza   +16 more
doaj   +1 more source

Regional and Historical Minerageny of the Gemstone Complexes in Russia (Quantitative Aspects) [PDF]

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2015
The paper presents an approximate quantitative estimation of the mineragenic potentials of gems in the paleogeodynamic systems, complexes, and geological formations of Russia, which are characterized by different age and regional distribution.
Polyanin V.S.   +3 more
doaj  

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