Results 61 to 70 of about 224,032 (261)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Estimation of the Measurement Accuracy of Wireless Passive Resonance Sensors
SensorsResonators are passive devices that respond to an excitation signal by oscillating at their natural frequency with exponentially decreasing amplitudes. Physical, chemical and electrical variables can modify the natural frequencies of resonators.
Leonhard M. Reindl +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sensors, 2013 In this paper, we address the problem of determining the optimal geometric configuration of an acoustic sensor network that will maximize the angle-related information available for underwater target positioning.
Joaquin Aranda +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Optomechanics-Based Quantum Estimation Theory for Collapse Models. [PDF]
Entropy (Basel), 2023 Marchese MM, Belenchia A, Paternostro M.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Object Detection and Tracking with YOLO and the Sliding Innovation Filter
SensorsObject detection and tracking are pivotal tasks in machine learning, particularly within the domain of computer vision technologies. Despite significant advancements in object detection frameworks, challenges persist in real-world tracking scenarios ...
Alexander Moksyakov +4 more
doaj +1 more source
Optimization of data acquisition operation in optical tomography based on estimation theory. [PDF]
Biomed Opt Express, 2021 Javidan M, Esfandi H, Pashaie R.
europepmc +1 more source