Results 71 to 80 of about 224,032 (261)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Modified CRLB Based Optimal Sampling Frequency Selection in Phase and Frequency Estimation
IEEE Access, 2019 The sampling process is an almost indispensable operation in signal processing. The sampling frequency is one of the factors in the sampling process and the selection of it is also important in the signal processing issues, such as detection, estimation,
Hao Wu, Yongqiang Cheng, Hongqiang Wang
doaj +1 more source
Multithreshold change plane model: Estimation theory and applications in subgroup identification. [PDF]
Stat Med, 2021 Li J, Li Y, Jin B, Kosorok MR.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cost-Optimized Video Dissemination Over Heterogeneous Cloud With SLAs Support
IEEE Access, 2019 A growing number of social video distribution services are turning toward to the cloud-based architecture for lower cost and better scalability. Although appealing, such a cloud content delivery network (cloud-based CDN) involves two key tasks: to ...
Zhiqiang Ruan, Xiucai Ye
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fiducial Theory and Invariant Estimation
The Annals of Mathematical Statistics, 1966 1 online resource (PDF, 18 pages)
Hora, Rajinder Bir, Buehler, Robert J.
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Multidimensional Polynomial Phase Estimation
IEEE Open Journal of Signal ProcessingAn estimation method is presented for polynomial phase signals, i.e., those adopting the form of a complex exponential whose phase is polynomial in its indices. Transcending the scope of existing techniques, the proposed estimator can handle an arbitrary
Heedong Do, Namyoon Lee, Angel Lozano
doaj +1 more source
Multi-radar target parameter estimation and fusion based on attribute scattering centre model
The Journal of Engineering, 2019 This study proposes a method of observing the same target from different radars to extract more useful target information, solving the problem of target occlusion in monostatic radar.
Chang Liu +3 more
doaj +1 more source