Results 131 to 140 of about 309,036 (359)

Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data [PDF]

arXiv, 2013
Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influence the rate and timing of gene expression. In this work we present a probabilistic model of transcription dynamics which is fitted to pol-II occupancy time course data measured using ChIP-Seq. The
arxiv  

Weak if any effect of estrogen on spatial memory in rats [PDF]

, 2002
In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Farkas, Tamás, Kis, Zsolt, Németh, Hajnalka, Toldi, József, Tóth, Tünde, Varga, Hedvig   +5 more
core  

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Sex hormones in Malay and Chinese men in Malaysia: are there age and race differences?

Clinics
OBJECTIVES: Variations in the prevalence of sex-hormone-related diseases have been observed between Asian ethnic groups living in the same country; however, available data concerning their sex hormone levels are limited.
Kok-Yong Chin, Ima-Nirwana Soelaiman, Isa Naina Mohamed, Fairus Ahmad, Elvy Suhana Mohd Ramli, Amilia Aminuddin, Wan Zurinah Wan Ngah   +6 more
doaj   +1 more source

Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. [PDF]

, 2018
Unbiased shRNA library screens revealed that the estrogen receptor-1 (ESR-1) is a key factor regulating HIV-1 latency. In both Jurkat T cells and a Th17 primary cell model for HIV-1 latency, selective estrogen receptor modulators (SERMs, i.e ...
Bacchetti, Peter, Chomont, Nicolas, Das, Biswajit, Deeks, Steven G, Dobrowolski, Curtis, Gandhi, Monica, Hoh, Rebecca, Johnston, Rowena, Karn, Jonathan, Luttge, Benjamin, Scully, Eileen, Valadkhan, Saba   +11 more
core  

Improving the Determination of Carbon Isotope Ratios of Endogenous Steroids Found in Human Serum

Drug Testing and Analysis, EarlyView.
A method employing high‐performance liquid chromatographic sample cleanup to determine the carbon isotope ratios of steroids found in human serum was developed and fully validated. A reference population encompassing more than 120 male and female athlete samples was investigated in order to establish population‐based thresholds for Δ‐values.
Thomas Piper, Mario Thevis
wiley   +1 more source

Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]

, 2013
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
A Grasselli, A Re, A Watahiki, Agnese Re, Alessandro Guffanti, Alfredo Pontecorvi, Antonella Farsetti, Armando Felsani, Arturo Londono-Vallejo, Aurora Aiello, BD Gehm, C Liu, C Zang, Carlo Gaetano, Claudia Colussi, Costanza Emanueli, CS Ross-Innes, D Bonci, D Fukumura, D Lodygin, DM Huffman, E Schreiber, G Garcia-Cardena, I Mattagajasingh, J Lu, J Veldscholte, JA Baur, JS Carroll, JS Horoszewicz, KH Lim, KP Porkka, L Ying, L Zeng, LJ Zhu, Luis Jaime Castro-Vega, M Yamakuchi, M Yamakuchi, Maurizio C. Capogrossi, MC Haigis, MD Kornberg, MD Robinson, ME Ritchie, MS Zaman, MV Iorio, N Hah, N Nadiminty, NR Bertos, OM Grober, P Gandellini, P Giovannelli, Q Wu, RT Prehn, S Anders, S Baranwal, S Kyo, S Misiti, S Nanni, S Nanni, S Nanni, S Volinia, Silvia Bacchetti, Simona Nanni, T Liu, T Vanhaecke, Valentina Benvenuti, W Fischle, Y Zhang   +66 more
core   +3 more sources

Determination of Hormonal Growth Promotants in Beef Using Liquid Chromatography–Tandem Mass Spectrometry

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed and validated to detect 12 synthetic or endogenous hormonal growth promotants commonly utilized in the livestock industry in the United States at low pg/mg concentrations. ABSTRACT Hormonal growth promotants (HGPs) are a class of pharmaceutical agents commonly administered to cattle in the United States to improve ...
Mary Mosburg, Yajing Li, Emily Helmes, Tara D. Falt, Josephine F. Trott, Gina Solomon, Russell C. Hovey, Benjamin C. Moeller   +7 more
wiley   +1 more source

Motif analysis of amphioxus, lamprey and invertebrate estrogen receptors and amphioxus and human estrogen-related receptors: Towards a better understanding of estrogen receptor evolution [PDF]

, 2008
*Background.* The origins of steroid-dependent regulation of the vertebrate estrogen receptor (ER) are poorly understood. Genes with statistically significant sequence similarity to vertebrate ERs have been found in lamprey, a basal vertebrate, and ...
Charlie Chandsawangbhuwana, Michael E. Baker   +1 more
core   +2 more sources

A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic [PDF]

, 1995
Sewage, a complex mixture of organic and inorganic chemicals, is considered to be a major source of environmental pollution. A random screen of 20 organic man-made chemicals present in liquid effluents revealed that half appeared able to interact with ...
Clark LB, Ema M, Ginsberg J, Henderson BE, Hites RA, J P Sumpter, Klinge KM, Kraybill HF, M G Parker, R White, S Jobling, Spelsberg TC, T Reynolds, Tzukerman MT, Verhagen H   +14 more
core   +2 more sources