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Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol.
New England Journal of Medicine, 2016 BACKGROUND Data suggest that estrogen-containing hormone therapy is associated with beneficial effects with regard to cardiovascular disease when the therapy is initiated temporally close to menopause but not when it is initiated later.
H. Hodis +12 more
semanticscholar +1 more source
Estradiol: micrograms or milligrams [PDF]
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Summary Estrogen is used to induce puberty in peripubertal girls with hypogonadism. Although both synthetic and natural forms are available, along with different routes of administration, in the UK oral ethinyl estradiol and the low-dose oral contraceptive pill are commonly used as hormone replacement therapy for practical reasons.
Jeremy Kirk +2 more
openaire +2 more sources
17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]
, 2016 Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N. +10 more
core +2 more sources
3D model of amphioxus steroid receptor complexed with estradiol [PDF]
, 2009 The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
David J. Chang, Michael E. Baker
core +2 more sources
Sex steroid application reverses changes in rat castration cells: Unbiased stereological analysis [PDF]
Archives of Biological Sciences, 2016 The aim of the present study was to examine the morphometric characteristics of folliclestimulating hormone (FSH) and luteinizing hormone (LH) immunoreactive cells in the pituitaries of orchidectomized (Orx) and Orx testosterone- or estradiol ...
Nestorović Nataša M. +7 more
doaj +1 more source
The role of estradiol in male reproductive function
Asian Journal of Andrology, 2016 Traditionally, testosterone and estrogen have been considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function.
Michael L. Schulster +2 more
semanticscholar +1 more source
PLoS ONE, 2020 The objective of this study was to evaluate predicting factors for supraphysiologic serum estradiol elevation during controlled ovarian stimulation (COS) with administration of letrozole and gonadotropins in patients with estrogen-dependent cancer.
Sung Woo Kim +5 more
doaj +1 more source
Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells [PDF]
, 2015 Estrogens and tamoxifen do not only exert their effects at the genomic level, but also play a role at the cell membrane activating downstream signaling pathways. We recently characterized an estrogen receptor-positive epithelial murine breast cancer cell
Bal, Elisa Dora +3 more
core +2 more sources
Systemic estradiol levels with low-dose vaginal estrogens
Menopause, 2019 Objectives: To critically evaluate published systemic estradiol levels during use of low-dose vaginal estrogens considering detection method and estrogen dose; describe challenges with accurately measuring estradiol; and determine the normal estradiol ...
R. Santen +3 more
semanticscholar +1 more source
Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. [PDF]
, 1993 associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging.
Krieg, Michael, Nass, Ralf, Tunn, Sabine
core +1 more source