Results 31 to 40 of about 309,036 (359)
BackgroundEndometrioid adenocarcinoma (EAC) is the most common subtype of endometrial cancer (EC) and is an estrogen-related cancer. In this study, we sought to investigate the expressions and mechanism of action of 17β-estradiol (E2) and long noncoding ...
Dan Qiao+6 more
doaj +1 more source
Estradiol activates PI3K/Akt/GSK3 pathway under chronic neurodegenerative conditions triggered by perinatal asphyxia [PDF]
Perinatal asphyxia (PA) remains as one of the most important causes of short-term mortality, psychiatric and neurological disorders in children, without an effective treatment.
Bellini, Maria Jose+3 more
core +2 more sources
Estradiol renal receptor molecules and estradiol-dependent antinatriuresis
Estradiol renal receptor molecules and estradiol-dependent antinatriuresis. A 35% decrease in urinary excretion of sodium was produced when 17β-estradiol was administered to adrenalectomized male rats in doses of 40 µg/day. Such estrogendependent retention of sodium independent of mineralocorticoid secretion suggests the possibility of a direct effect ...
James H. Ludens+2 more
openaire +3 more sources
Gonadotropin inhibitory hormone (GnIH) prevents the ‘priming’ effect of estradiol-17β
GnIH inhibits GnRH-stimulated gonadotropin secretion in the sheep by action on the pituitary gonadotropes. Estradiol-17β(E2) also acts at the level of the pituitary gonadotrope to exert negative and positive feedback effects on ...
Ika Puspita Sari+3 more
doaj +1 more source
AMH Regulation by Steroids in the Mammalian Testis: Underlying Mechanisms and Clinical Implications
Anti-Müllerian hormone (AMH) is a distinctive biomarker of the immature Sertoli cell. AMH expression, triggered by specific transcription factors upon fetal Sertoli cells differentiation independently of gonadotropins or sex steroids, drives Müllerian ...
Nadia Y. Edelsztein+5 more
doaj +1 more source
Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals [PDF]
The aim of this study was to compare results obtained by eight different short-term assays of estrogenlike actions of chemicals conducted in 10 different laboratories in five countries. Twenty chemicals were selected to represent direct-acting estrogens,
Ana M. Soto+34 more
core +2 more sources
In vitro fertilization (IVF) is an effective means to treat infertility, but the pregnancy rate is still unsatisfactory and reliable markers to predict pregnancy outcome are ill-defined.
Cong Hu+5 more
doaj +1 more source
To facilitate the development of broad-spectrum retina neuroprotectants that can be delivered through topical dosage forms, this proteomics study focused on analyzing target engagements through the identification of functional protein networks impacted ...
Laszlo Prokai+3 more
doaj +1 more source
A joint modeling approach to study the association between subject-level longitudinal marker variabilities and repeated outcomes [PDF]
Women are at increased risk of bone loss during the menopausal transition; in fact, nearly 50\% of women's lifetime bone loss occurs during this time. The longitudinal relationships between estradiol (E2) and follicle-stimulating hormone (FSH), two hormones that change have characteristic changes during the menopausal transition, and bone health ...
arxiv
The objective of this study was to determine the effect of long-term (48 days), per os administration of specific zearalenone (ZEN) doses (20 and 40 μg ZEN/kg BW in experimental groups EI and EII, which were equivalent to 200% and 400% of the upper ...
Łukasz Zielonka+4 more
doaj +1 more source