Results 191 to 200 of about 341,736 (266)

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Metabolic Endotoxemia Amplifies Estrogen Signaling Through Stromal Crosstalk in Obesity-Associated Breast Cancer. [PDF]

Int J Mol Sci
Drai E, Nahmias Blank D, Hermano E, Yifrach A, Chen O, Maimon O, Popovtzer A, Peretz T, Meirovitz A, Elkin M.   +9 more
europepmc   +1 more source

Effect of esomeprazole on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study is to evaluate the effects of multiple doses of esomeprazole, a strong proton pump inhibitor and acid‐reducing agent, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader.
Lana Tran, Naihan Chen, Jennifer A. Winton, Kyle T. Matschke, Smita P. Goodman, Kimberly C. Lee, Yuanyuan Zhang, Weiwei Tan   +7 more
wiley   +1 more source

Association Between Hormone Replacement Therapy and Incidence of Tendon Injuries and Surgical Repair in Perimenopausal Women: A Propensity Score-Matched National Cohort Study. [PDF]

Orthop J Sports Med
Bcharah G, Cancio-Bello A, Iturregui-Pastrana JM, Elsabbagh Z, Le Y, Nguyen C, Karsen PJ, Patel KA, Chhabra AS.   +8 more
europepmc   +1 more source

Influence of Menopause Onset on the Progression of Lumbar Degenerative Disease: A Clinical Correlation Study. [PDF]

J Orthop Case Rep
Ganguly S, Kumar S, Alsaifi MS, Aggarwal P, Naseeha P, Shreyas CS.   +5 more
europepmc   +1 more source

Estrogen Replacement Therapy in Ovariectomized Rats: Complementary Roles of ER and GPR30 in Alleviating Depressive-like Behavior. [PDF]

Curr Issues Mol Biol
He S, Ren Z, Wu L, Xie Y, Sun L, Xiao L, Wang G.   +6 more
europepmc   +1 more source

Impact of Salvadora persica aqueous extract on follicular development in female rats. [PDF]

Biol Res
Ghareeb SM, Abd-Elkareem M, Abou-Elmagd A.   +2 more
europepmc   +1 more source

Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha. [PDF]

MicroPubl Biol
Elzaghir R, Collins KC, Abdulshafi A, Ismail M, Asleh N, Saeed M, Galarza-Ramirez DE, Valladares E, Lewis A, Mena S, Pizzo A, Shyti A, Najor NA, Abdel Latif MK, Livezey MR.   +14 more
europepmc   +1 more source