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Estrogens, estrogen receptors and melanoma

Expert Review of Anticancer Therapy, 2011
The skin is the largest nonreproductive target tissue on which estrogen plays many beneficial and protective roles. Although neither exogenous hormones nor pregnancy represent significant risk factors for melanoma, epidemiological data suggest a higher survival rate in women with metastatic disease versus men and in premenopausal versus postmenopausal ...
Vincenzo De Giorgi   +8 more
openaire   +3 more sources

BIOSYNTHESIS OF ESTROGENS

Obstetrical & Gynecological Survey, 1962
The formation of estrogens and phenolic material from a large number of do Cis, C19 and C2i steroids and related structures has been investigated, employing a human placental microsomal preparation supplemented with TPNH and oxygen. The data from the incubation of 2 C 14-labeled androgens are included.
C, GUAL   +4 more
openaire   +2 more sources

The Role of Estrogen and Estrogen Receptors in Chemoresistance

Current Medicinal Chemistry, 2011
Drug resistance is one of the major obstacles limiting the success of cancer chemotherapy. Biological mechanisms contributing to drug resistance may be present de novo and related to inherent features or may be raised after exposure to anticancer drugs. In recent years, both clinical observations and experimental studies suggested that steroid hormones
M, Sui, H, Zhang, W, Fan
openaire   +2 more sources

Enzymatic treatment of estrogens and estrogen glucuronide

Journal of Environmental Sciences, 2009
Natural and synthetic estrogens from sewage treatment systems are suspected to influence the reproductive health of the animals in the rivers. In this article, we investigated the enzymatic treatment of three estrogens (estrone, 17beta-estradiol, and 17alpha-ethynyletstradiol) by a fungal laccase which oxidize phenolic compounds with dissolved oxygen ...
Takaaki, Tanaka   +6 more
openaire   +2 more sources

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