Results 201 to 210 of about 741,345 (366)

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science, EarlyView.
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
wiley   +1 more source

Review of hormonal replacement therapy options for the treatments of menopausal symptoms. [PDF]

Korean J Fam Med
Edelweishia M, Christoper A, Theresia E, Angelia V.   +3 more
europepmc   +1 more source

Dermovascular Action of Estrogen, The Ovarian Follicular Hormone11Read before the 3rd Annual Meeting of the Society for Investigative Dermatology, New York, June 11, 1940.

, 1941
Samuel R. M. Reynolds
openalex   +1 more source

THE ESTROGEN-LIKE SUBSTANCES IN CERTAIN LEGUMES AND GRASSES: II. THE EFFECT OF STAGE OF MATURITY AND FREQUENCY OF CUTTING ON THE ESTROGENIC ACTIVITY OF SOME FORAGES [PDF]

, 1959
W. D. Kitts, A. J. Wood, E. E. Swierstra, V. C. Brink   +3 more
openalex   +1 more source

Phloretin, A Weak Estrogen and Estrogen Antagonist

Experimental Biology and Medicine, 1963
Aleck Borman, Leonard J. Lerner, Turkheimer Ar   +2 more
openaire   +3 more sources

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

Advanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan, Yi Ran, Hong Pan, Qinnan Yan, Wenjing Zhang, Bo Zhou, Pengzhi Xu, Rongdong Liao, Haipeng Xue, Will Jiang, Tailin He, Qingyun Jia, Lei Qin, Francis Y Lee, Di Chen, Chuanju Liu, Guozhi Xiao   +16 more
wiley   +1 more source

Cardiovascular Risk Associated with Menopause and Menopause Hormone Therapy: A Review and Contemporary Approach to Risk Assessment. [PDF]

Curr Atheroscler Rep
D'Costa Z, Spertus E, Hingorany S, Patil R, Horwich T, Press MC, Shah J, Watson KE, Jafari L.   +8 more
europepmc   +1 more source

TOPICAL ESTROGENS: CLINICAL EFFECTS AND SIDE ACTIONS [PDF]

, 1952
Irving Shapiro
openalex   +1 more source

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Understanding Problematic Bleeding When Using Contraception: Guidance for Clinicians. [PDF]

Open Access J Contracept
Barretta M, Grandi G.
europepmc   +1 more source