Results 31 to 40 of about 996,617 (405)
Sex-dependent influence of endogenous estrogen in pulmonary hypertension [PDF]
, 2014 Rationale: The incidence of pulmonary arterial hypertension (PAH) is greater in women suggesting estrogens may play a role in the disease pathogenesis. Experimentally, in males exogenously administered estrogen can protect against PH; however in models ...
Audrey F. Wright +17 more
core +1 more source
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
International Journal of Molecular Sciences, 2019 In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window of receptivity.
R. Marquardt +3 more
semanticscholar +1 more source
Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
, 2010 Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
core +1 more source
Biology of Sex Differences, 2017 Epidemiologic studies have previously suggested that premenopausal females have reduced incidence of cardiovascular disease (CVD) when compared to age-matched males, and the incidence and severity of CVD increases postmenopause.
Andrea Iorga +5 more
semanticscholar +1 more source
The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders
International Journal of Molecular Sciences, 2020 Increasing evidence suggests estrogen and estrogen signaling pathway disturbances across psychiatric disorders. Estrogens are not only crucial in sexual maturation and reproduction but are also highly involved in a wide range of brain functions, such as ...
W. Hwang +3 more
semanticscholar +1 more source
Sex-specific differences in primary Sjögren's disease
Frontiers in Dental Medicine, 2023 Many autoimmune diseases show a striking female sex predilection, including primary Sjögren's disease (pSD). Patients with pSD display exocrine gland pathology, such as salivary hypofunction and salivary and lacrimal gland inflammation.
Achamaporn Punnanitinont, Jill M. Kramer
doaj +1 more source
Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer [PDF]
, 2009 Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells.
Arata Shimo +10 more
core +2 more sources
Journal of Cellular Physiology, 2007 AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J, Cheskis +3 more
openaire +2 more sources
Frontiers in Molecular Neuroscience, 2022 Environmental enrichment (EE) is a promising therapeutic strategy in improving metabolic and neuronal responses, especially due to its non-invasive nature. However, the exact mechanism underlying the sex-differential effects remains unclear.
Soonil Pyo +13 more
doaj +1 more source
Effect of Estrogen on Musculoskeletal Performance and Injury Risk
Frontiers in Physiology, 2019 Estrogen has a dramatic effect on musculoskeletal function. Beyond the known relationship between estrogen and bone, it directly affects the structure and function of other musculoskeletal tissues such as muscle, tendon, and ligament.
Nkechinyere Chidi-Ogbolu, K. Baar
semanticscholar +1 more source