Results 41 to 50 of about 982,336 (407)

Developmental Effects of Prenatal Exposure to Bisphenol A on the Uterus of Rat Offspring

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
Exposure to estrogenic compounds during critical periods of fetal development could result in adverse effects on the development of reproductive organs that are not apparent until later in life.
Gilbert Schönfelder   +3 more
doaj   +1 more source

Estrogen receptor as the predictive factor for response to chemotherapy in breast cancer [PDF]

open access: yesArchive of Oncology, 2006
It has generally been accepted that breast cancer (BC) cells are equally responsive to chemotherapy (CHT) irrespective of ER status. However, subset analyses of disease outcome in recently reported trials on neoadjuvant and adjuvant CHT brought new ...
Šušnjar Snežana   +1 more
doaj   +1 more source

The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders

open access: yesInternational Journal of Molecular Sciences, 2020
Increasing evidence suggests estrogen and estrogen signaling pathway disturbances across psychiatric disorders. Estrogens are not only crucial in sexual maturation and reproduction but are also highly involved in a wide range of brain functions, such as ...
W. Hwang   +3 more
semanticscholar   +1 more source

Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain

open access: yesFrontiers in Endocrinology, 2012
Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
doaj   +1 more source

Effect of Estrogen on Musculoskeletal Performance and Injury Risk

open access: yesFrontiers in Physiology, 2019
Estrogen has a dramatic effect on musculoskeletal function. Beyond the known relationship between estrogen and bone, it directly affects the structure and function of other musculoskeletal tissues such as muscle, tendon, and ligament.
Nkechinyere Chidi-Ogbolu, K. Baar
semanticscholar   +1 more source

Hysterectomy for Benign Indications and Risk of Cataract Formation in South Korean Women

open access: yesMedicina, 2023
Background and Objectives: Few studies have investigated the relationship between female reproductive hormones, especially estrogen, and the incidence of cataracts.
Jae Suk Kim
doaj   +1 more source

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

open access: yes, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki   +8 more
core   +1 more source

Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview

open access: yesCells
The endometrium is crucial for the perpetuation of human species. It is a complex and dynamic tissue lining the inner wall of the uterus, regulated throughout a woman’s life based on estrogen and progesterone fluctuations.
Isabelle Dias Da Silva   +3 more
doaj   +1 more source

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone

open access: yesMolecules, 2023
Estradiol (E2) plays an important role in the progression of diseases such as breast cancer and endometriosis. Inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1), the enzyme that catalyzes the last step in the biosynthesis of the estrogenic
Adrien Djiemeny Ngueta   +3 more
doaj   +1 more source

Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]

open access: yes, 2017
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core   +1 more source

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