Results 41 to 50 of about 759,583 (365)

Molecular mechanism of estrogen–estrogen receptor signaling [PDF]

Reproductive Medicine and Biology, 2016
Abstract17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and estrogen receptor (ER)α and ERβ that are encoded by distinct genes.
Yasar, Pelin, Ayaz, Gamze, User, Sirma Damla, Gupur, Gizem, Muyan, Mesut   +4 more
openaire   +3 more sources

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica, Jonak, Carrie R, Kauffman, Alexander S, Xie, Changchuan   +3 more
core   +1 more source

Estrogenic Activities in Rodent Estrogen-Free Diets [PDF]

Endocrinology, 2005
Diets lacking soy and alpha-alpha derivatives that are considered to be estrogen-free by standard bioassays (uterotrophic assay and vaginal opening) have been revealed to contain considerable amounts of compounds able to transcriptionally activate the estrogen receptors (ERs) and stimulate luciferase expression in several organs of the ERE-Luc reporter
P. Ciana, A. Brena, P. Sparaciari, E. Bonetti, D. Di Lorenzo, A. Maggi   +5 more
openaire   +3 more sources

Estrogenic activity, race/ethnicity, and Indigenous American ancestry among San Francisco Bay Area women. [PDF]

, 2019
Estrogens play a significant role in breast cancer development and are not only produced endogenously, but are also mimicked by estrogen-like compounds from environmental exposures.
Fejerman, Laura, Gomez, Scarlett L, John, Esther M, Sanchez, Sylvia S, Smith, Martyn T, Stanczyk, Frank Z, Tachachartvanich, Phum   +6 more
core   +2 more sources

A rapidly enlarging cutaneous hemangioma in pregnancy

Clinics and Practice, 2014
This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient’s thumb during her pregnancy. This was excised and identified as a hemangioma.
Marwan Ma’ayeh, Nikhil Purandare, Michelle Harrison, Michael P. Geary   +3 more
doaj   +1 more source

Increased prevalence of colorectal adenomas in women with breast cancer [PDF]

, 2005
Background: The frequency of colorectal adenomas and carcinomas was investigated in a large cohort of women with breast cancer in comparison with matched controls, since data on the occurrence of second tumors in women with breast cancer is controversial.
Bayerdörffer, Ekkehard, Eiermann, Wolfgang, Göke, Burkhard, Mannes, Gerd Alexander, Meining, Alexander, Ochsenkühn, Thomas, Sackmann, Michael, Späth, Lydia, Wiebecke, Baldur   +8 more
core   +1 more source

Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes [PDF]

, 2009
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review.
Ahel M., Andersen H., Baronti C., Belfroid A. C., Birkett J. W., Burke M., Carballa M., Carballa M., Chiu T. Y., Clara M., Davenport R. J., D’Ascenzo G., Fürhacker M., Gaulk L. S., Giger W., Gomes R. L., Gomes R. L., Gomes R. L., Graham D. W., Holbrook R. D., Ifelebuegu A. O., Janex-Habibi M. L., Jobling S., Jobling S., Johnson A. C., Johnson A. C., Jones O. A. H., Joss A., Kirk L. A., Koh K., Koh Y. K. K., Koh Y. K. K., Koh Y. K. K., Kreuzinger N., Lagana A., Lai K. M., Lai K. M., Langford K., Langford K. H., Loyo-Rosales J. E., Nakada N., Obeng L. A., Onda K., Quinlivan P. A., Ren Y.-X., Renner R., Rosenfeldt E. J., Routledge E. J., Servos M. R., Snyder S. A., Stephenson T., Svenson A., Ternes T. A., Ternes T. A., Ternes T. A., Vader J. S.   +55 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Supplementation of 17β-Estradiol Normalizes Rapid Gastric Emptying by Restoring Impaired Nrf2 and nNOS Function in Obesity-Induced Diabetic Ovariectomized Mice

Antioxidants, 2020
Gastroparesis (Gp) is a multifactorial condition commonly observed in females and is characterized by delayed or rapid gastric emptying (GE). The role of ovarian hormones on GE in the pathogenesis of obesity induced type 2 diabetes mellitus (T2DM) is ...
Jeremy C. Sprouse, Chethan Sampath, Pandu R. Gangula   +2 more
doaj   +1 more source

Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]

, 1989
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla, A Mode, A Schleusener, AE Pegg, AJ Syms, B Katchen, CL Mendenhall, CW Bardin, D Kahn, DM Cohen, E Bresnidk, E Mezey, E Mezey, E Mezey, EM Higgins, ER Lax, F Neumann, J Simard, J Terblanche, JA Gustafsson, JA Gustafsson, JA McGowan, JH Clark, JM Kissane, JP Blondeau, KE Crow, LE Porter, M Kayfman, M Sarff, MF Zuretti, OH Lowry, PK Eagon, PK Eagon, PK Eagon, R Neri, W Welshons, WJ King   +36 more
core   +1 more source