Estrogen-Independent Activation of Estrogen Receptors [PDF]
Hypertension, 2011 See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer +2 more
openaire +3 more sources
A Teleost Fish Model to Understand Hormonal Mechanisms of Non-breeding Territorial Behavior
Frontiers in Endocrinology, 2020 Aggressive behaviors occurring dissociated from the breeding season encourage the search of non-gonadal underlying regulatory mechanisms. Brain estrogen has been shown to be a key modulator of this behavior in bird and mammal species, and it remains to ...
Ana C. Silva +4 more
doaj +1 more source
A mathematical model of Breast cancer (ER+) with excess estrogen: Mixed treatments using Ketogenic diet, endocrine therapy and Immunotherapy [PDF]
arXiv, 2022 Breast Cancer is a major public health problem and the most common diagnosed malignancy in woman. There have been significant developments in clinical approaches and theoretical experimental to understand the interactions of cancer cells dynamics with the immune system, also developments on analytical and computational models to help provide insights ...
arxiv
A simple and robust method for connecting small-molecule drugs using gene-expression signatures [PDF]
BMC Bioinformatics 2008, 9:258, 2008 Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar pharmacological or toxicological properties.
arxiv +1 more source
Estrogen plus progestin and the risk of coronary heart disease.
New England Journal of Medicine, 2003 BACKGROUND Recent randomized clinical trials have suggested that estrogen plus progestin does not confer cardiac protection and may increase the risk of coronary heart disease (CHD).
J. Manson +14 more
semanticscholar +1 more source
Bioaugmentation mitigates the impact of estrogen on coliform-grazing protozoa in slow sand filters [PDF]
, 2016 Exposure to endocrine-disrupting chemicals (EDCs), such as estrogens, is a growing issue for human and animal health as they have been shown to cause reproductive and developmental abnormalities in wildlife and plants and have been linked to male ...
Collins, Gavin +3 more
core +10 more sources
Signal Pathway of Estrogen and Estrogen Receptor in the Development of Thyroid Cancer
Frontiers in Oncology, 2021 The molecular mechanisms underlying the development of thyroid cancer (TC) have been examined through extensive experiments. A large number of studies have shown that the incidences of thyroid cancer in women is much higher than that in men, so estrogen ...
Jian Liu +3 more
doaj +1 more source
FMO Study of the Interaction Energy between Human Estrogen Receptor $α$ and Selected Ligands [PDF]
arXiv, 2022 Fragment molecular orbital (FMO) calculations were performed in aqueous media which allowed us to obtain the interaction energy between the human estrogen receptor $\alpha$ ligand-binding domain (ER) and the selected ligands (L): 17$\beta$-estradiol (E2), 17$\alpha$-estradiol (17$\alpha$-E2), estriol (E3), genistein (GNT), diethylstilbestrol (DES ...
arxiv
Statistical adjustment for a measure of healthy lifestyle doesn't yield the truth about hormone therapy [PDF]
IMS Collections 2008, Vol. 2, 142-152, 2008 The Women's Health Initiative randomized clinical trial of hormone therapy found no benefit of hormones in preventive cardiovascular disease, a finding in striking contrast with a large body of observational research. Understanding whether better methodology and/or statistical adjustment might have prevented the erroneous conclusions of observational ...
arxiv +1 more source
Effect of Estrogen on Musculoskeletal Performance and Injury Risk
Frontiers in Physiology, 2019 Estrogen has a dramatic effect on musculoskeletal function. Beyond the known relationship between estrogen and bone, it directly affects the structure and function of other musculoskeletal tissues such as muscle, tendon, and ligament.
Nkechinyere Chidi-Ogbolu, K. Baar
semanticscholar +1 more source