Estrogen-Independent Activation of Estrogen Receptors [PDF]
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer +2 more
openaire +3 more sources
Estrogen Signaling in Endometrial Cancer: a Key Oncogenic Pathway with Several Open Questions
Endometrial cancer is the most common gynecological cancer in the developed world, and it is one of the few cancer types that is becoming more prevalent and leading to more deaths in the USA each year. The majority of endometrial tumors are considered to
Adriana C. Rodriguez +3 more
semanticscholar +1 more source
Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria +5 more
core +1 more source
It has become increasingly apparent that the pain threshold of females and males varies in an estrogen dependent manner. To investigate the modulation of pain by estrogen and the molecular mechanisms involved in this process.
Guanghui An +3 more
semanticscholar +1 more source
Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]
Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi +5 more
core +1 more source
Estrogen receptor cytochemistry by fluorescent estrogen. [PDF]
A recently synthesized fluorescein-labeled estrogen (17FE, 1-(N)-fluoresceinyl-estrone-thiosemicarbazone) interacts with estrogen-target cells like the native hormone and visualizes the uptake, transport, and distribution of estrogen in intact target cells.
G. Fabris +5 more
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Estrogen, Stress, and Depression: Cognitive and Biological Interactions.
This article reviews the interactions of estrogen changes and psychosocial stress in contributing to vulnerability to major depressive disorder (MDD) in women.
Kimberly M Albert, P. Newhouse
semanticscholar +1 more source
Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR +10 more
core +1 more source
A rapidly enlarging cutaneous hemangioma in pregnancy
This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient’s thumb during her pregnancy. This was excised and identified as a hemangioma.
Marwan Ma’ayeh +3 more
doaj +1 more source
AbstractBy regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the receptor activity, its interaction with other proteins and DNA.
Boris J. Cheskis +3 more
openaire +3 more sources

